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MT-ATP8 mitochondrially encoded ATP synthase 8 [ Homo sapiens (human) ]

Gene ID: 4509, updated on 22-May-2022

Summary

Official Symbol
MT-ATP8provided by HGNC
Official Full Name
mitochondrially encoded ATP synthase 8provided by HGNC
Primary source
HGNC:HGNC:7415
See related
MIM:516070; AllianceGenome:HGNC:7415
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ATPase8; MTATP8; ATP8
Summary
Contributes to proton-transporting ATP synthase activity, rotational mechanism. Involved in mitochondrial ATP synthesis coupled proton transport. Part of mitochondrial proton-transporting ATP synthase complex. Implicated in multiple sclerosis and urinary bladder cancer. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See MT-ATP8 in Genome Data Viewer
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) MT (non-nuclear) NC_012920.1 (8366..8572)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) MT (non-nuclear) NC_012920.1 (8366..8572)

Chromosome MT - NC_012920.1Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase subunit II Neighboring gene tRNA-Lys Neighboring gene ATP synthase F0 subunit 6 Neighboring gene cytochrome c oxidase subunit III Neighboring gene tRNA-Gly

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

General protein information

Preferred Names
ATP synthase F0 subunit 8
YP_003024030.1
  • ATP synthase 8; ATPase subunit 8

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_012920.1 Reference assembly

    Range
    8366..8572
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_003024030.1 ATP synthase F0 subunit 8 (mitochondrion) [Homo sapiens]

    See identical proteins and their annotated locations for YP_003024030.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P03928
    UniProtKB/TrEMBL
    U5YV54
    Related
    ENSP00000355265.1
    Conserved Domains (1) summary
    MTH00102
    Location:167
    ATP8; ATP synthase F0 subunit 8; Validated