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GGNBP1 gametogenetin binding protein 1 (pseudogene) [ Homo sapiens (human) ]

Gene ID: 449520, updated on 9-Jun-2025
Official Symbol
GGNBP1provided by HGNC
Official Full Name
gametogenetin binding protein 1 (pseudogene)provided by HGNC
Primary source
HGNC:HGNC:19427
See related
MIM:609495; AllianceGenome:HGNC:19427
Gene type
pseudo
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This gene is the ortholog of the mouse gametogenetin-binding protein 1 gene. In human, the open reading frame is disrupted by a nonsense mutation after 8-aa; consequently, this gene is currently considered to be a unitary pseudogene in human even though it is functional in other mammals. [provided by RefSeq, Aug 2009]
Expression
Biased expression in testis (RPKM 1.5), lymph node (RPKM 0.2) and 2 other tissues See more
Orthologs
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See GGNBP1 in Genome Data Viewer
Location:
6p21.31
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (33583699..33589026)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (33404889..33410216)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (33551476..33556803)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_91452 Neighboring gene RNA, 7SL, cytoplasmic 26, pseudogene Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_91454 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24361 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:33546627-33547272 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33552868-33553862 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr6:33557672-33558871 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:33559025-33559664 Neighboring gene BCL2 antagonist/killer 1 Neighboring gene long intergenic non-protein coding RNA 336 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:33560945-33561584 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24366 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33566996-33567496 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33567497-33567997 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33571503-33572004 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33572005-33572504 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr6:33574668-33575174 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:33575775-33576317 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33577246-33577832 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33577833-33578418 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17047 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17049 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17048 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:33589316-33589501 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33590023-33590572 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33590573-33591121 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17051 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33597027-33597903 Neighboring gene uncharacterized LOC124901305 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17052 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33602349-33602895 Neighboring gene inositol 1,4,5-trisphosphate receptor type 3 Neighboring gene ITPR3 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33618418-33618918 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33618919-33619419 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:33624122-33624658 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:33625731-33626265 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33626906-33627416 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33636045-33636676 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33636677-33637307 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33641013-33641534 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33658493-33659470 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:33659471-33660446 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:33660447-33661424 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr6:33662237-33663436 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:33665333-33666308 Neighboring gene microRNA 3934 Neighboring gene ubiquinol-cytochrome c reductase complex assembly factor 2

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
Products Interactant Other Gene Complex Source Pubs Description

Markers

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_028361.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AY383627, Z93017

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    33583699..33589026
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    33404889..33410216
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001005478.1: Suppressed sequence

    Description
    NM_001005478.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.