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Hsp70Ab Heat-shock-protein-70Ab [ Drosophila melanogaster (fruit fly) ]

Gene ID: 44920, updated on 18-Sep-2020

Summary

Official Symbol
Hsp70Abprovided by FlyBase
Official Full Name
Heat-shock-protein-70Abprovided by FlyBase
Primary source
FLYBASE:FBgn0013276
Locus tag
Dmel_CG18743
Gene type
protein coding
RNA name
Heat-shock-protein-70Ab
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG18743; dhsp70; dHsp70; Dm-hsp70; Dmel\CG18743; DMHSP7A2; GRP78; hs70; hsp 70; Hsp 70; hsp-70; Hsp-70; hsp70; Hsp70; HSP70; hsp70 87A; hsp70(87A); Hsp70-Ab; hsp70a; hsp70A; Hsp70A; hsp70Ab; Hsp70ab; Hsp70aB; HSP70Ab; Hsp70b

Genomic context

See Hsp70Ab in Genome Data Viewer
Location:
87A3-87A3; 3-51 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11958535..11960909)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7784257..7786631)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Heat-shock-protein-70Aa Neighboring gene uncharacterized protein Neighboring gene aurora A Neighboring gene uncharacterized protein Neighboring gene Glutamate Carrier 1 Neighboring gene Transport and Golgi organization 9

Genomic regions, transcripts, and products

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the Hsp70Ab gene: The Hsp70Ab gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, zebrafish, S.cerevisiae, K.lactis, E.gossypii, A.thaliana, and frog.
  • Orthologs

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
heat shock protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
misfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding involved in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
cellular response to unfolded protein IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chaperone cofactor-dependent protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
heat shock-mediated polytene chromosome puffing IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to heat IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to heat NAS
Non-traceable Author Statement
more info
PubMed 
response to hypoxia IEP
Inferred from Expression Pattern
more info
PubMed 
response to hypoxia IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to unfolded protein IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to unfolded protein NAS
Non-traceable Author Statement
more info
PubMed 
vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
Heat-shock-protein-70Ab
Names
87A locus
CG18743-PA
Hsp70Ab-PA
heat shock 70
heat shock protein 70
heat shock protein 70Ab
heat-shock protein 70
protein 70
NP_524798.2

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    11958535..11960909
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_080059.3NP_524798.2  Heat-shock-protein-70Ab [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524798.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P02825, P82910
    Related
    FBpp0081956, FBtr0082482
    Conserved Domains (2) summary
    cd10233
    Location:3379
    HSPA1-2_6-8-like_NBD; Nucleotide-binding domain of HSPA1-A, -B, -L, HSPA-2, -6, -7, -8, and similar proteins
    PTZ00009
    Location:2642
    PTZ00009; heat shock 70 kDa protein; Provisional
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