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DNApol-alpha60 DNA polymerase alpha 60kD [ Drosophila melanogaster (fruit fly) ]

Gene ID: 44915, updated on 27-Feb-2020

Summary

Official Symbol
DNApol-alpha60provided by FlyBase
Official Full Name
DNA polymerase alpha 60kDprovided by FlyBase
Primary source
FLYBASE:FBgn0259676
Locus tag
Dmel_CG5553
Gene type
protein coding
RNA name
DNA polymerase alpha 60kD
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:GM13640; CG5553; Dmel\CG5553; Dmpol alpha; DNA polalpha; DNAprim; DNAprimase; GM13640; l(3)77ABe; l(3)j10B2; Pol; pol alpha; polalpha; Polalpha 60 kDa; PRI2; S(faf)240

Genomic context

See DNApol-alpha60 in Genome Data Viewer
Location:
77B-77B6; 3-47 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.26 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (20359833..20361585, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (20352933..20354685, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene kin17 Neighboring gene uncharacterized protein Neighboring gene Toll-9 Neighboring gene inturned

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the DNApol-alpha60 gene: The DNApol-alpha60 gene is conserved in human, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
DNA replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
DNA replication, synthesis of RNA primer IDA
Inferred from Direct Assay
more info
PubMed 
DNA-dependent DNA replication IDA
Inferred from Direct Assay
more info
PubMed 
compound eye morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic cell cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
alpha DNA polymerase:primase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
alpha DNA polymerase:primase complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
DNA polymerase alpha 60kD
Names
CG5553-PA
DNA polymerase alpha 58,000 beta subunit
DNA polymerase alpha 60,000 beta subunit
DNA primase
DNA replication primer
DNApol-alpha60-PA
DNAprim
NP_652001.2

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    20359833..20361585 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143744.4NP_652001.2  DNA polymerase alpha 60kD [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_652001.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VPH2
    UniProtKB/TrEMBL
    I1WYG8
    Related
    FBpp0077899, FBtr0078241
    Conserved Domains (1) summary
    cd07322
    Location:30459
    PriL_PriS_Eukaryotic; Eukaryotic core primase: Large subunit, PriL
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