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LCE6A late cornified envelope 6A [ Homo sapiens (human) ]

Gene ID: 448835, updated on 13-May-2022

Summary

Official Symbol
LCE6Aprovided by HGNC
Official Full Name
late cornified envelope 6Aprovided by HGNC
Primary source
HGNC:HGNC:31824
See related
Ensembl:ENSG00000235942 AllianceGenome:HGNC:31824
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C1orf44
Summary
Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward skin (RPKM 51.7) See more
Orthologs
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Genomic context

See LCE6A in Genome Data Viewer
Location:
1q21.3
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (152842856..152843983)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (151979414..151980541)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (152815332..152816459)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene late cornified envelope 1B Neighboring gene late cornified envelope 1A Neighboring gene uncharacterized LOC105371444 Neighboring gene late cornified envelope 7A

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General protein information

Preferred Names
late cornified envelope protein 6A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001128600.2NP_001122072.1  late cornified envelope protein 6A

    See identical proteins and their annotated locations for NP_001122072.1

    Status: VALIDATED

    Source sequence(s)
    BG210316, DQ991251
    Consensus CDS
    CCDS44227.1
    UniProtKB/Swiss-Prot
    A0A183
    Related
    ENSP00000411070.2, ENST00000431011.3
    Conserved Domains (1) summary
    pfam15858
    Location:177
    LCE6A; Late cornified envelope protein 6A family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    152842856..152843983
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017001327.2XP_016856816.1  late cornified envelope protein 6A isoform X1

    UniProtKB/Swiss-Prot
    A0A183
    Conserved Domains (1) summary
    pfam15858
    Location:177
    LCE6A; Late cornified envelope protein 6A family

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    151979414..151980541
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)