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CCL25 C-C motif chemokine ligand 25 [ Canis lupus familiaris (dog) ]

Gene ID: 448798, updated on 27-Jun-2026
Official Symbol
CCL25provided by VGNC
Official Full Name
C-C motif chemokine ligand 25provided by VGNC
Primary source
VGNC:VGNC:38887
See related
Ensembl:ENSCAFG00845028954 RGD:12270307
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See CCL25 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (53217788..53250217)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (52520955..52523887)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (53126468..53129402)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (52450071..52453004)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (52894798..52897724)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111091386 Neighboring gene ELAV like RNA binding protein 1 Neighboring gene fibrillin 3 Neighboring gene 40S ribosomal protein S2-like

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables CCR chemokine receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chemokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to interleukin-1 IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to tumor necrosis factor IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to type II interferon IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lymphocyte chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monocyte chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neutrophil chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
C-C motif chemokine 25
Names
CC chemokine ligand 25
small-inducible cytokine A25

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005259.1 → NP_001005259.1  C-C motif chemokine 25 precursor

    See identical proteins and their annotated locations for NP_001005259.1

    Status: PROVISIONAL

    Source sequence(s)
    AB164617
    UniProtKB/Swiss-Prot
    Q68A93
    UniProtKB/TrEMBL
    A0A8I3Q1S2
    Conserved Domains (1) summary
    pfam00048
    Location:27 → 88
    IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    53217788..53250217
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038426393.1 → XP_038282321.1  C-C motif chemokine 25 isoform X2

    UniProtKB/Swiss-Prot
    Q68A93
    UniProtKB/TrEMBL
    A0A8I3Q1S2
    Conserved Domains (1) summary
    pfam00048
    Location:27 → 88
    IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

  2. XM_038426391.1 → XP_038282319.1  C-C motif chemokine 25 isoform X2

    UniProtKB/Swiss-Prot
    Q68A93
    UniProtKB/TrEMBL
    A0A8I3Q1S2
    Conserved Domains (1) summary
    pfam00048
    Location:27 → 88
    IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

  3. XM_038426390.1 → XP_038282318.1  C-C motif chemokine 25 isoform X2

    UniProtKB/Swiss-Prot
    Q68A93
    UniProtKB/TrEMBL
    A0A8I3Q1S2
    Conserved Domains (1) summary
    pfam00048
    Location:27 → 88
    IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

  4. XM_038426389.1 → XP_038282317.1  C-C motif chemokine 25 isoform X2

    UniProtKB/Swiss-Prot
    Q68A93
    UniProtKB/TrEMBL
    A0A8I3Q1S2
    Conserved Domains (1) summary
    pfam00048
    Location:27 → 88
    IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

  5. XM_038426392.1 → XP_038282320.1  C-C motif chemokine 25 isoform X2

    UniProtKB/Swiss-Prot
    Q68A93
    UniProtKB/TrEMBL
    A0A8I3Q1S2
    Conserved Domains (1) summary
    pfam00048
    Location:27 → 88
    IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

  6. XM_038426388.1 → XP_038282316.1  C-C motif chemokine 25 isoform X1

    UniProtKB/TrEMBL
    A0A8I3Q1S2, A0A8I3S6Y5
    Related
    ENSCAFP00845040171.1, ENSCAFT00845051219.1
    Conserved Domains (1) summary
    pfam00048
    Location:40 → 101
    IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

  7. XM_038426396.1 → XP_038282324.1  C-C motif chemokine 25 isoform X2

    UniProtKB/Swiss-Prot
    Q68A93
    UniProtKB/TrEMBL
    A0A8I3Q1S2
    Conserved Domains (1) summary
    pfam00048
    Location:27 → 88
    IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

  8. XM_038426395.1 → XP_038282323.1  C-C motif chemokine 25 isoform X2

    UniProtKB/Swiss-Prot
    Q68A93
    UniProtKB/TrEMBL
    A0A8I3Q1S2
    Conserved Domains (1) summary
    pfam00048
    Location:27 → 88
    IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

  9. XM_038426394.1 → XP_038282322.1  C-C motif chemokine 25 isoform X2

    UniProtKB/Swiss-Prot
    Q68A93
    UniProtKB/TrEMBL
    A0A8I3Q1S2
    Conserved Domains (1) summary
    pfam00048
    Location:27 → 88
    IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

  10. XM_038426397.1 → XP_038282325.1  C-C motif chemokine 25 isoform X2

    UniProtKB/Swiss-Prot
    Q68A93
    UniProtKB/TrEMBL
    A0A8I3Q1S2
    Related
    ENSCAFP00845040189.1, ENSCAFT00845051243.1
    Conserved Domains (1) summary
    pfam00048
    Location:27 → 88
    IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

RNA

  1. XR_005297400.1 RNA Sequence

  2. XR_005297397.1 RNA Sequence

  3. XR_005297401.1 RNA Sequence

  4. XR_005297399.1 RNA Sequence

  5. XR_005297402.1 RNA Sequence

  6. XR_005297398.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    52450071..52453004
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    52894798..52897724
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    53126468..53129402
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    52520955..52523887
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q68A93.1 GenPept UniProtKB/Swiss-Prot:Q68A93

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