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chit1 chitinase 1 (chitotriosidase) [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 448265, updated on 14-Nov-2024

Summary

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Official Symbol
chit1provided by Xenbase
Official Full Name
chitinase 1 (chitotriosidase)provided by Xenbase
Primary source
Xenbase:XB-GENE-5801457
See related
Ensembl:ENSXETG00000011844 AllianceGenome:Xenbase:XB-GENE-5801457
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
chio
Summary
Predicted to enable chitin binding activity and chitinase activity. Predicted to act upstream of or within carbohydrate metabolic process and chitin catabolic process. Predicted to be located in extracellular region. Orthologous to human OVGP1 (oviductal glycoprotein 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See chit1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
12
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (70698928..70709837, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 2 NC_030678.1 (62327334..62338237, complement)

Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 49 Neighboring gene ciliary microtubule associated protein 3 Neighboring gene TATA-box binding protein associated factor 8 Neighboring gene bystin like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. New paralogues and revised time line in the expansion of the vertebrate GH18 family. Hussain M, et al. J Mol Evol, 2013 Apr. PMID 23558346
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC89015

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables chitin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chitin binding IEA
Inferred from Electronic Annotation
more info
  
enables chitinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chitinase activity IEA
Inferred from Electronic Annotation
more info
  
enables endochitinase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in chitin catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within chitin catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within polysaccharide catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
chitotriosidase-1
NP_001005792.1
XP_031751711.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005792.1 → NP_001005792.1  chitotriosidase-1 precursor

    See identical proteins and their annotated locations for NP_001005792.1

    Status: PROVISIONAL

    Source sequence(s)
    BC075332
    UniProtKB/TrEMBL
    A0A803K921, F6RI22, Q6DJ52
    Related
    ENSXETP00000025889.3, ENSXETT00000025889.5
    Conserved Domains (2) summary
    cd02872
    Location:24 → 386
    GH18_chitolectin_chitotriosidase; This conserved domain family includes a large number of catalytically inactive chitinase-like lectins (chitolectins) including YKL-39, YKL-40 (HCGP39), YM1, oviductin, and AMCase (acidic mammalian chitinase), as well as catalytically active ...
    pfam01607
    Location:442 → 491
    CBM_14; Chitin binding Peritrophin-A domain

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    70698928..70709837 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031895851.1 → XP_031751711.1  chitotriosidase-1 isoform X1

    UniProtKB/TrEMBL
    A0A803K921, F6RI22, Q6DJ52
    Conserved Domains (2) summary
    cd02872
    Location:24 → 386
    GH18_chitolectin_chitotriosidase; This conserved domain family includes a large number of catalytically inactive chitinase-like lectins (chitolectins) including YKL-39, YKL-40 (HCGP39), YM1, oviductin, and AMCase (acidic mammalian chitinase), as well as catalytically active ...
    pfam01607
    Location:442 → 491
    CBM_14; Chitin binding Peritrophin-A domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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