U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

rhoa ras homolog family member A [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 448080, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
rhoaprovided by Xenbase
Official Full Name
ras homolog family member Aprovided by Xenbase
Primary source
Xenbase:XB-GENE-489222
See related
Ensembl:ENSXETG00000005934 AllianceGenome:Xenbase:XB-GENE-489222
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
arha; arh12; rho12; xrhoa; rhoa-a; rhoa-b; rhoh12
Summary
Predicted to enable GTP binding activity and GTPase activity. Predicted to act upstream of or within skeletal muscle satellite cell migration and wound healing, spreading of cells. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in breast carcinoma. Orthologous to human RHOA (ras homolog family member A). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See rhoa in Genome Data Viewer
Location:
chromosome: 4
Exon count:
6
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (125856053..125871243, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (115431294..115446465, complement)

Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene chromosome 4 C3orf62 homolog Neighboring gene glutathione peroxidase 1 Neighboring gene uncharacterized LOC105947715 Neighboring gene aminomethyltransferase

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC69542

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in Rho protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell migration IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within skeletal muscle satellite cell migration ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
  
involved_in stress fiber assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within wound healing, spreading of cells ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cleavage furrow IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in dendritic spine IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
transforming protein RhoA
Names
ras homolog gene family, member A
NP_001004825.1
XP_012819967.1
XP_012819968.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004825.1 → NP_001004825.1  transforming protein RhoA

    See identical proteins and their annotated locations for NP_001004825.1

    Status: PROVISIONAL

    Source sequence(s)
    BC074607
    UniProtKB/TrEMBL
    A0A6I8T126, Q6GL96
    Conserved Domains (1) summary
    cl21455
    Location:1 → 98
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    125856053..125871243 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012964514.3 → XP_012819968.1  transforming protein RhoA isoform X1

    See identical proteins and their annotated locations for XP_012819968.1

    UniProtKB/TrEMBL
    A0A6I8QLE9, Q28GJ8
    Conserved Domains (1) summary
    cd01870
    Location:5 → 179
    RhoA_like; Ras homology family A (RhoA)-like includes RhoA, RhoB and RhoC

  2. XM_012964513.3 → XP_012819967.1  transforming protein RhoA isoform X1

    See identical proteins and their annotated locations for XP_012819967.1

    UniProtKB/TrEMBL
    A0A6I8QLE9, Q28GJ8
    Related
    ENSXETP00000056826.2, ENSXETT00000056826.4
    Conserved Domains (1) summary
    cd01870
    Location:5 → 179
    RhoA_like; Ras homology family A (RhoA)-like includes RhoA, RhoB and RhoC
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.