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rab4b RAB4B, member RAS oncogene family [ Danio rerio (zebrafish) ]

Gene ID: 445498, updated on 2-Nov-2024

Summary

Official Symbol
rab4bprovided by ZNC
Official Full Name
RAB4B, member RAS oncogene familyprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040822-15
See related
Ensembl:ENSDARG00000012177 AllianceGenome:ZFIN:ZDB-GENE-040822-15
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:101015
Summary
Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in regulation of endocytosis and vesicle-mediated transport. Predicted to act upstream of or within Rab protein signal transduction and protein transport. Predicted to be located in early endosome membrane and plasma membrane. Predicted to be active in insulin-responsive compartment and recycling endosome. Orthologous to human RAB4B (RAB4B, member RAS oncogene family). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See rab4b in Genome Data Viewer
Location:
chromosome: 15
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (8813755..8856348, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (8837684..8880277, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 35a Neighboring gene adaptor related protein complex 2 subunit sigma 1 Neighboring gene ras homolog family member Ub Neighboring gene reticulon 2a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables G protein activity IEA
Inferred from Electronic Annotation
more info
 
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within Rab protein signal transduction IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in early endosome membrane IEA
Inferred from Electronic Annotation
more info
 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
is_active_in insulin-responsive compartment IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in recycling endosome IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
ras-related protein Rab-4B
NP_001004002.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004002.1NP_001004002.1  ras-related protein Rab-4B

    See identical proteins and their annotated locations for NP_001004002.1

    Status: PROVISIONAL

    Source sequence(s)
    BC080219
    UniProtKB/Swiss-Prot
    Q68EK7
    Related
    ENSDARP00000020980.8, ENSDART00000008273.9
    Conserved Domains (2) summary
    smart00175
    Location:9172
    RAB; Rab subfamily of small GTPases
    cd04113
    Location:9169
    Rab4; Rab GTPase family 4 (Rab4)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    8813755..8856348 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)