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itga2b integrin, alpha 2b [ Danio rerio (zebrafish) ]

Gene ID: 445380, updated on 8-Nov-2020

Summary

Official Symbol
itga2bprovided by ZNC
Official Full Name
integrin, alpha 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-051031-1
See related
Ensembl:ENSDARG00000018687
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
GP; si:dkey-27b3.6
Orthologs

Genomic context

See itga2b in Genome Data Viewer
Location:
chromosome: 3
Exon count:
30
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (21350509..21382399, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (21219961..21251851, complement)
103 previous assembly Zv9 (GCF_000002035.4) 3 NC_007114.5 (21563570..21595460, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene synaptogyrin 1a Neighboring gene family with sequence similarity 171 member A2a Neighboring gene aquaporin-5-like Neighboring gene uncharacterized LOC108182815 Neighboring gene corticotropin releasing hormone receptor 1

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
blood coagulation IGI
Inferred from Genetic Interaction
more info
PubMed 
blood coagulation IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
endothelial cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integrin complex IDA
Inferred from Direct Assay
more info
PubMed 
integrin complex IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
integrin alpha-IIb
Names
CD41
GPIIb
glycoprotein IIb
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003857.1NP_001003857.1  integrin alpha-IIb

    See identical proteins and their annotated locations for NP_001003857.1

    Status: PROVISIONAL

    Source sequence(s)
    AY319286
    UniProtKB/TrEMBL
    Q6EIY7
    Related
    ENSDARP00000013339.9, ENSDART00000016562.11
    Conserved Domains (2) summary
    smart00191
    Location:376429
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam08441
    Location:475908
    Integrin_alpha2; Integrin alpha

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    21350509..21382399 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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