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TARP TCR gamma alternate reading frame protein [ Homo sapiens (human) ]

Gene ID: 445347, updated on 9-Jun-2025
Gene symbol
TARP
Gene description
TCR gamma alternate reading frame protein
See related
Ensembl:ENSG00000289746 MIM:609642
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CD3G
Summary
In some non-lymphoid tissues, the unrearranged T cell receptor gamma (TRG@) locus is expressed. The resulting transcript contains a subset of the TRG@ gene segments and is shorter than TRG@ transcripts expressed in lymphoid tissues. This RefSeq record represents the unrearranged TRG@ locus transcript; the complete TRG@ locus is represented by the genomic RefSeq NG_001336. The transcript represented by this RefSeq has two open reading frames (ORFs) that encode different proteins. The downstream ORF is in the same frame as TRG@ and its protein product is similar to TRG@ proteins. The upstream ORF uses a different reading frame and encodes a novel protein. [provided by RefSeq, Jul 2008]
Expression
Biased expression in prostate (RPKM 38.4), bone marrow (RPKM 13.6) and 3 other tissues See more
Orthologs
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See TARP in Genome Data Viewer
Location:
7p14.1
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (38259643..38273636, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (38416644..38430635, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (38299244..38313237, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene T cell receptor gamma locus Neighboring gene T cell receptor gamma joining 2 Neighboring gene T cell receptor gamma joining P2 Neighboring gene T cell receptor gamma constant 1 Neighboring gene T cell receptor gamma joining 1 Neighboring gene T cell receptor gamma joining P Neighboring gene T cell receptor gamma joining P1 Neighboring gene T cell receptor gamma variable 11 (non-functional)

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
Products Interactant Other Gene Complex Source Pubs Description
Preferred Names
T-cell receptor gamma alternate reading frame protein
Names
TCR- gamma V-IV
antigen, T-cell receptor

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029035.1 RefSeqGene

    Range
    5001..19005
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
  2. NG_001336.3 

    Range
    105005..118998
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001003799.2NP_001003799.1  T-cell receptor gamma alternate reading frame protein isoform 1

    See identical proteins and their annotated locations for NP_001003799.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) uses the upstream ORF. The resulting protein (isoform 1) localizes to the outer mitochondrial membrane.
    Source sequence(s)
    AF151103, BF674593
    Consensus CDS
    CCDS94087.1
    UniProtKB/Swiss-Prot
    A2JGV3
    Related
    ENSP00000513628.1, ENST00000698248.1
  2. NM_001003806.2NP_001003806.1  T-cell receptor gamma alternate reading frame protein isoform 2

    See identical proteins and their annotated locations for NP_001003806.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) uses the downstream ORF. The resulting protein (isoform 2) is similar to but shorter than TRG@ proteins, since this transcript does not include any variable regions.
    Source sequence(s)
    AF151103, BF674593
    UniProtKB/TrEMBL
    Q0VGM3
    Conserved Domains (1) summary
    cl11960
    Location:144
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    38259643..38273636 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    38416644..38430635 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)