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rpp21 ribonuclease P subunit p21 [ Danio rerio (zebrafish) ]

Gene ID: 445136, updated on 9-Sep-2025
Official Symbol
rpp21provided by ZNC
Official Full Name
ribonuclease P subunit p21provided by ZNC
Primary source
ZFIN:ZDB-GENE-040801-37
See related
Ensembl:ENSDARG00000043404 AllianceGenome:ZFIN:ZDB-GENE-040801-37
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:100862
Summary
Predicted to enable metal ion binding activity and ribonuclease P activity. Predicted to be involved in tRNA processing. Predicted to act upstream of or within tRNA 5'-leader removal. Predicted to be located in cytoplasm. Predicted to be part of nucleolar ribonuclease P complex. Orthologous to human RPP21 (ribonuclease P/MRP subunit p21). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
human mouse all
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See rpp21 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 22 NC_133197.1 (15144873..15152451, complement)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 22 NC_007133.7 (15429655..15437237, complement)

Chromosome 22 - NC_133197.1Genomic Context describing neighboring genes Neighboring gene ribosomal RNA processing 36 Neighboring gene transmembrane protein 264 Neighboring gene glypican 5b Neighboring gene glypican 1a Neighboring gene ankyrin repeat and MYND domain containing 1

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. Identification of differentially expressed genes between cloned and zygote-developing zebrafish (Danio rerio) embryos at the dome stage using suppression subtractive hybridization. Luo D, et al. Biol Reprod, 2009 Apr. PMID 19092113
  2. Inventory and analysis of the protein subunits of the ribonucleases P and MRP provides further evidence of homology between the yeast and human enzymes. Rosenblad MA, et al. Nucleic Acids Res, 2006. PMID 16998185, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables endonuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables ribonuclease P activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within RNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in RNA processing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within tRNA 5'-leader removal IEA
Inferred from Electronic Annotation
more info
  
involved_in tRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within tRNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of endoribonuclease complex IEA
Inferred from Electronic Annotation
more info
  
part_of nucleolar ribonuclease P complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonuclease P complex IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
ribonuclease P protein subunit p21
Names
ribonuclease P 21 subunit
rpp2
NP_001003530.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003530.2 → NP_001003530.1  ribonuclease P protein subunit p21

    See identical proteins and their annotated locations for NP_001003530.1

    Status: PROVISIONAL

    Source sequence(s)
    BC078300
    UniProtKB/TrEMBL
    Q6DBZ7
    Related
    ENSDARP00000063718.4, ENSDART00000063719.5
    Conserved Domains (1) summary
    pfam04032
    Location:13 → 97
    Rpr2; RNAse P Rpr2/Rpp21/SNM1 subunit domain

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133197.1 Reference GRCz12tu Primary Assembly

    Range
    15144873..15152451 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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