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pigo.L phosphatidylinositol glycan anchor biosynthesis class O L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444225, updated on 4-Jan-2025

Summary

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Official Symbol
pigo.L
Official Full Name
phosphatidylinositol glycan anchor biosynthesis class O L homeolog
Primary source
Xenbase:XB-GENE-5945147
Locus tag
XELAEV_18008523mg
See related
EnsemblRapid:ENSXLAG00005001407 AllianceGenome:Xenbase:XB-GENE-5945147
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
pigo
Summary
Predicted to enable mannose-ethanolamine phosphotransferase activity. Predicted to act upstream of or within GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hyperphosphatasia with impaired intellectual development syndrome 2. Orthologous to human PIGO (phosphatidylinositol glycan anchor biosynthesis class O). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See pigo.L in Genome Data Viewer
Location:
chromosome: 1L
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1L NC_054371.1 (228980889..228999340)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1L NC_030724.1 (215539902..215558298)

Chromosome 1L - NC_054371.1Genomic Context describing neighboring genes Neighboring gene kinesin family member 24 L homeolog Neighboring gene ubiquitin associated protein 1 L homeolog Neighboring gene kinesin family member 27 S homeolog Neighboring gene von Willebrand factor A domain containing 5A, gene 2 L homeolog Neighboring gene PHD finger protein 24 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC80777

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables mannose-ethanolamine phosphotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within GPI anchor biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
phosphatidylinositol glycan anchor biosynthesis class O L homeolog
Names
GPI ethanolamine phosphate transferase 3
phosphatidylinositol glycan anchor biosynthesis, class O

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092329.1 → NP_001085798.1  phosphatidylinositol glycan anchor biosynthesis class O L homeolog

    See identical proteins and their annotated locations for NP_001085798.1

    Status: PROVISIONAL

    Source sequence(s)
    BC073359
    UniProtKB/TrEMBL
    A0A974I6B5, Q6GNZ1
    Related
    ENSXLAP00005004268.1, ENSXLAT00005004334.1
    Conserved Domains (2) summary
    COG1524
    Location:36 → 282
    Npp1; Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily [General function prediction only]
    cd16023
    Location:63 → 338
    GPI_EPT_3; GPI ethanolamine phosphate transferase 3, PIG-O

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    228980889..228999340
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041580255.1 → XP_041436189.1  phosphatidylinositol glycan anchor biosynthesis class O L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1M3B3, A0A974I6B5
    Related
    ENSXLAP00005004266.1, ENSXLAT00005004332.1
    Conserved Domains (1) summary
    cd16023
    Location:63 → 338
    GPI_EPT_3; GPI ethanolamine phosphate transferase 3, PIG-O
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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