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AKT3 AKT serine/threonine kinase 3 [ Canis lupus familiaris (dog) ]

Gene ID: 442964, updated on 25-Jul-2026
Official Symbol
AKT3provided by VGNC
Official Full Name
AKT serine/threonine kinase 3provided by VGNC
Primary source
VGNC:VGNC:37773
See related
Ensembl:ENSCAFG00845004858 RGD:12362272
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See AKT3 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
20
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 7 NC_051811.1 (34462499..34769046, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 7 NC_006589.4 (34110532..34416684, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 7 NC_049228.1 (34580988..34887190, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 7 NC_049267.1 (34299283..34606536, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 7 NC_049748.1 (34316186..34622902, complement)

Chromosome 7 - NC_051811.1Genomic Context describing neighboring genes Neighboring gene SHH signaling and ciliogenesis regulator SDCCAG8 Neighboring gene uncharacterized LOC119872541 Neighboring gene uncharacterized LOC119872540 Neighboring gene zinc finger CCCH domain-containing protein 15-like Neighboring gene uncharacterized LOC111096694 Neighboring gene uncharacterized LOC111096697 Neighboring gene uncharacterized LOC111096695

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
RAC-gamma serine/threonine-protein kinase
Names
protein kinase B gamma-like protein
v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
XP_005622653.1
XP_022276846.1
XP_022276848.1
XP_022276849.1
XP_022276850.1
XP_022276851.1
XP_038337300.1
XP_038337301.1
XP_038337302.1
XP_038337303.1
XP_038337304.1
XP_038337305.1
XP_038337306.1
XP_038337307.1
XP_038398657.1
XP_038398658.1
XP_038398659.1
XP_038398660.1
XP_038398661.1
XP_038398662.1
XP_038398663.1
XP_038398664.1
XP_038424227.1
XP_038424253.1
XP_038462804.1
XP_038462805.1
XP_038462806.1
XP_038462807.1
XP_038462808.1
XP_038462809.1
XP_038462810.1
XP_038462811.1
XP_038462812.1
XP_038527480.1
XP_038527481.1
XP_038527482.1
XP_038527483.1
XP_038527484.1
XP_038527485.1
XP_038527486.1
XP_038527487.1

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051811.1 Reference ROS_Cfam_1.0

    Range
    34462499..34769046 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038671558.1 → XP_038527486.1  RAC-gamma serine/threonine-protein kinase isoform X7

    UniProtKB/TrEMBL
    A0A8I3MMB4
    Conserved Domains (2) summary
    cd05593
    Location:90 → 437
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)
    cl17171
    Location:4 → 68
    PH-like; Pleckstrin homology-like domain

  2. XM_038671555.1 → XP_038527483.1  RAC-gamma serine/threonine-protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8C0JH30, A0A8I3MV00, A0A8I3MV10
    Related
    ENSCAFP00845006866.1, ENSCAFT00845008707.1
    Conserved Domains (2) summary
    cd01241
    Location:4 → 110
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:132 → 479
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  3. XM_038671553.1 → XP_038527481.1  RAC-gamma serine/threonine-protein kinase isoform X2

    UniProtKB/TrEMBL
    A0A8I3MV10
    Conserved Domains (2) summary
    cd01241
    Location:15 → 123
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:145 → 492
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  4. XM_038671554.1 → XP_038527482.1  RAC-gamma serine/threonine-protein kinase isoform X3

    UniProtKB/TrEMBL
    A0A8I3MMB4
    Conserved Domains (2) summary
    cd01241
    Location:56 → 150
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cl21453
    Location:172 → 496
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038671552.1 → XP_038527480.1  RAC-gamma serine/threonine-protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8I3MMB4
    Conserved Domains (2) summary
    cd01241
    Location:56 → 150
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:172 → 519
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  6. XM_038671559.1 → XP_038527487.1  RAC-gamma serine/threonine-protein kinase isoform X8

    UniProtKB/TrEMBL
    A0A8I3MMB4
    Conserved Domains (2) summary
    cd05593
    Location:71 → 418
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)
    cl17171
    Location:1 → 49
    PH-like; Pleckstrin homology-like domain

  7. XM_038671556.1 → XP_038527484.1  RAC-gamma serine/threonine-protein kinase isoform X5

    UniProtKB/TrEMBL
    A0A8I3MV10
    Conserved Domains (2) summary
    cd01241
    Location:1 → 102
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:124 → 471
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  8. XM_038671557.1 → XP_038527485.1  RAC-gamma serine/threonine-protein kinase isoform X6

    UniProtKB/TrEMBL
    A0A8I3MPC6
    Related
    ENSCAFP00845006886.1, ENSCAFT00845008734.1
    Conserved Domains (2) summary
    cd01241
    Location:56 → 150
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cl21453
    Location:192 → 459
    PKc_like; Protein Kinases, catalytic domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049267.1 Alternate UMICH_Zoey_3.1

    Range
    34299283..34606536 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038481378.1 → XP_038337306.1  

    Conserved Domains (2) summary
    cd05593
    Location:90 → 437
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)
    cl17171
    Location:4 → 68
    PH-like; Pleckstrin homology-like domain

  2. XM_038481375.1 → XP_038337303.1  

    Conserved Domains (2) summary
    cd01241
    Location:4 → 110
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:132 → 479
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  3. XM_038481373.1 → XP_038337301.1  

    Conserved Domains (2) summary
    cd01241
    Location:15 → 123
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:145 → 492
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  4. XM_038481374.1 → XP_038337302.1  

    Conserved Domains (2) summary
    cd01241
    Location:56 → 150
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cl21453
    Location:172 → 496
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038481372.1 → XP_038337300.1  

    Conserved Domains (2) summary
    cd01241
    Location:56 → 150
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:172 → 519
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  6. XM_038481379.1 → XP_038337307.1  

    Conserved Domains (2) summary
    cd05593
    Location:71 → 418
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)
    cl17171
    Location:1 → 49
    PH-like; Pleckstrin homology-like domain

  7. XM_038481376.1 → XP_038337304.1  

    Conserved Domains (2) summary
    cd01241
    Location:1 → 102
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:124 → 471
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  8. XM_038481377.1 → XP_038337305.1  

    Conserved Domains (2) summary
    cd01241
    Location:56 → 150
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cl21453
    Location:192 → 459
    PKc_like; Protein Kinases, catalytic domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049748.1 Alternate UNSW_CanFamBas_1.0

    Range
    34316186..34622902 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038606883.1 → XP_038462811.1  

    Conserved Domains (2) summary
    cd05593
    Location:90 → 437
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)
    cl17171
    Location:4 → 68
    PH-like; Pleckstrin homology-like domain

  2. XM_038606879.1 → XP_038462807.1  

    Conserved Domains (2) summary
    cd01241
    Location:4 → 110
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:132 → 479
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  3. XM_038606880.1 → XP_038462808.1  

    Conserved Domains (2) summary
    cd01241
    Location:4 → 110
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:132 → 479
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  4. XM_038606877.1 → XP_038462805.1  

    Conserved Domains (2) summary
    cd01241
    Location:15 → 123
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:145 → 492
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  5. XM_038606878.1 → XP_038462806.1  

    Conserved Domains (2) summary
    cd01241
    Location:56 → 150
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cl21453
    Location:172 → 496
    PKc_like; Protein Kinases, catalytic domain

  6. XM_038606876.1 → XP_038462804.1  

    Conserved Domains (2) summary
    cd01241
    Location:56 → 150
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:172 → 519
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  7. XM_038606884.1 → XP_038462812.1  

    Conserved Domains (2) summary
    cd05593
    Location:71 → 418
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)
    cl17171
    Location:1 → 49
    PH-like; Pleckstrin homology-like domain

  8. XM_038606881.1 → XP_038462809.1  

    Conserved Domains (2) summary
    cd01241
    Location:1 → 102
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:124 → 471
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  9. XM_038606882.1 → XP_038462810.1  

    Conserved Domains (2) summary
    cd01241
    Location:56 → 150
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cl21453
    Location:192 → 459
    PKc_like; Protein Kinases, catalytic domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049228.1 Alternate UU_Cfam_GSD_1.0

    Range
    34580988..34887190 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038542735.1 → XP_038398663.1  RAC-gamma serine/threonine-protein kinase isoform X7

    UniProtKB/TrEMBL
    A0A8I3MMB4
    Conserved Domains (2) summary
    cd05593
    Location:90 → 437
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)
    cl17171
    Location:4 → 68
    PH-like; Pleckstrin homology-like domain

  2. XM_038542732.1 → XP_038398660.1  RAC-gamma serine/threonine-protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8C0JH30, A0A8I3MV00, A0A8I3MV10
    Conserved Domains (2) summary
    cd01241
    Location:4 → 110
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:132 → 479
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  3. XM_038542730.1 → XP_038398658.1  RAC-gamma serine/threonine-protein kinase isoform X2

    UniProtKB/TrEMBL
    A0A8I3MV10
    Conserved Domains (2) summary
    cd01241
    Location:15 → 123
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:145 → 492
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  4. XM_038542731.1 → XP_038398659.1  RAC-gamma serine/threonine-protein kinase isoform X3

    UniProtKB/TrEMBL
    A0A8I3MMB4
    Conserved Domains (2) summary
    cd01241
    Location:56 → 150
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cl21453
    Location:172 → 496
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038542729.1 → XP_038398657.1  RAC-gamma serine/threonine-protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8I3MMB4
    Conserved Domains (2) summary
    cd01241
    Location:56 → 150
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:172 → 519
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  6. XM_038542736.1 → XP_038398664.1  RAC-gamma serine/threonine-protein kinase isoform X8

    UniProtKB/TrEMBL
    A0A8I3MMB4
    Conserved Domains (2) summary
    cd05593
    Location:71 → 418
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)
    cl17171
    Location:1 → 49
    PH-like; Pleckstrin homology-like domain

  7. XM_038542733.1 → XP_038398661.1  RAC-gamma serine/threonine-protein kinase isoform X5

    UniProtKB/TrEMBL
    A0A8I3MV10
    Conserved Domains (2) summary
    cd01241
    Location:1 → 102
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:124 → 471
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  8. XM_038542734.1 → XP_038398662.1  RAC-gamma serine/threonine-protein kinase isoform X6

    UniProtKB/TrEMBL
    A0A8I3MPC6
    Conserved Domains (2) summary
    cd01241
    Location:56 → 150
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cl21453
    Location:192 → 459
    PKc_like; Protein Kinases, catalytic domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006589.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    34110532..34416684 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038568325.1 → XP_038424253.1  RAC-gamma serine/threonine-protein kinase isoform X7

    UniProtKB/TrEMBL
    A0A8I3MMB4
    Conserved Domains (2) summary
    cd05593
    Location:90 → 437
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)
    cl17171
    Location:4 → 68
    PH-like; Pleckstrin homology-like domain

  2. XM_038568299.1 → XP_038424227.1  RAC-gamma serine/threonine-protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8C0JH30, A0A8I3MV00, A0A8I3MV10
    Conserved Domains (2) summary
    cd01241
    Location:4 → 110
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:132 → 479
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  3. XM_022421140.2 → XP_022276848.1  RAC-gamma serine/threonine-protein kinase isoform X2

    UniProtKB/TrEMBL
    A0A8I3MV10
    Conserved Domains (2) summary
    cd01241
    Location:15 → 123
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:145 → 492
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  4. XM_022421141.2 → XP_022276849.1  RAC-gamma serine/threonine-protein kinase isoform X3

    UniProtKB/TrEMBL
    A0A8I3MMB4
    Conserved Domains (2) summary
    cd01241
    Location:56 → 150
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cl21453
    Location:172 → 496
    PKc_like; Protein Kinases, catalytic domain

  5. XM_022421138.2 → XP_022276846.1  RAC-gamma serine/threonine-protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8I3MMB4
    Conserved Domains (2) summary
    cd01241
    Location:56 → 150
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:172 → 519
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  6. XM_005622596.4 → XP_005622653.1  RAC-gamma serine/threonine-protein kinase isoform X8

    See identical proteins and their annotated locations for XP_005622653.1

    UniProtKB/TrEMBL
    A0A8I3MMB4
    Conserved Domains (2) summary
    cd05593
    Location:71 → 418
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)
    cl17171
    Location:1 → 49
    PH-like; Pleckstrin homology-like domain

  7. XM_022421142.2 → XP_022276850.1  RAC-gamma serine/threonine-protein kinase isoform X5

    UniProtKB/TrEMBL
    A0A8I3MV10
    Conserved Domains (2) summary
    cd01241
    Location:1 → 102
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cd05593
    Location:124 → 471
    STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

  8. XM_022421143.1 → XP_022276851.1  RAC-gamma serine/threonine-protein kinase isoform X6

    UniProtKB/TrEMBL
    A0A8I3MPC6
    Conserved Domains (2) summary
    cd01241
    Location:56 → 150
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
    cl21453
    Location:192 → 459
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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