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ZNF727 zinc finger protein 727 [ Homo sapiens (human) ]

Gene ID: 442319, updated on 23-Nov-2021

Summary

Official Symbol
ZNF727provided by HGNC
Official Full Name
zinc finger protein 727provided by HGNC
Primary source
HGNC:HGNC:22785
See related
Ensembl:ENSG00000214652
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF727P
Expression
Broad expression in thyroid (RPKM 2.3), ovary (RPKM 1.5) and 21 other tissues See more
Orthologs
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Genomic context

See ZNF727 in Genome Data Viewer
Location:
7q11.21
Exon count:
5
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (64043194..64085339)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (63505812..63545717)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 1005 Neighboring gene uncharacterized LOC105375317 Neighboring gene tripartite motif containing 60 pseudogene 17 Neighboring gene GUSB pseudogene 6 Neighboring gene MT-ND4L pseudogene 2 Neighboring gene MT-ND4 pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
putative zinc finger protein 727
Names
zinc finger protein 727 pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159522.3NP_001152994.1  putative zinc finger protein 727

    See identical proteins and their annotated locations for NP_001152994.1

    Status: VALIDATED

    Source sequence(s)
    AC115220, DA235663
    Consensus CDS
    CCDS55113.1
    UniProtKB/Swiss-Prot
    A8MUV8
    Related
    ENSP00000485448.1, ENST00000456806.3
    Conserved Domains (6) summary
    smart00349
    Location:464
    KRAB; krueppel associated box
    COG5048
    Location:226409
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:286306
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:148167
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:443
    KRAB; KRAB box
    pfam13465
    Location:382407
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    64043194..64085339
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017012225.2XP_016867714.1  putative zinc finger protein 727 isoform X1

RNA

  1. XR_242241.3 RNA Sequence

  2. XR_927469.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_011772.1: Suppressed sequence

    Description
    NG_011772.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
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