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GALNTL6 polypeptide N-acetylgalactosaminyltransferase like 6 [ Homo sapiens (human) ]

Gene ID: 442117, updated on 1-Aug-2020

Summary

Official Symbol
GALNTL6provided by HGNC
Official Full Name
polypeptide N-acetylgalactosaminyltransferase like 6provided by HGNC
Primary source
HGNC:HGNC:33844
See related
Ensembl:ENSG00000174473 MIM:615138
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GALNT17; GALNACT20; GalNAc-T6L
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See GALNTL6 in Genome Data Viewer
Location:
4q34.1
Exon count:
21
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (171812656..173041559)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (172734575..173961559)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105377535 Neighboring gene long intergenic non-protein coding RNA 2174 Neighboring gene uncharacterized LOC441052 Neighboring gene uncharacterized LOC105377537 Neighboring gene ubiquitin conjugating enzyme E2 N pseudogene Neighboring gene GALNTL6 antisense RNA 1 Neighboring gene uncharacterized LOC107986201 Neighboring gene uncharacterized LOC101930370 Neighboring gene RNA, 7SL, cytoplasmic 253, pseudogene Neighboring gene polypeptide N-acetylgalactosaminyltransferase 7 Neighboring gene microRNA 548t

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC44629

Gene Ontology Provided by GOA

Function Evidence Code Pubs
carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
polypeptide N-acetylgalactosaminyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
protein O-linked glycosylation via threonine IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
polypeptide N-acetylgalactosaminyltransferase-like 6
Names
GaNTase 17
GalNAc transferase 17
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 17
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 20
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
galNAc-T17
polypeptide GalNAc transferase 17
polypeptide GalNAc transferase-like 6
pp-GaNTase 17
protein-UDP acetylgalactosaminyltransferase 17
putative polypeptide N-acetylgalactosaminyltransferase 17
NP_001030017.2
XP_011530295.1
XP_011530296.1
XP_011530297.1
XP_011530298.1
XP_011530299.1
XP_016863732.1
XP_016863733.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034845.3NP_001030017.2  polypeptide N-acetylgalactosaminyltransferase-like 6

    See identical proteins and their annotated locations for NP_001030017.2

    Status: VALIDATED

    Source sequence(s)
    AC025561, AC131952, AJ626725, BX108658
    Consensus CDS
    CCDS34104.1
    UniProtKB/Swiss-Prot
    Q49A17
    UniProtKB/TrEMBL
    E5D8G0
    Related
    ENSP00000423313.1, ENST00000506823.6
    Conserved Domains (4) summary
    cd02510
    Location:143438
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    cd00161
    Location:456584
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00652
    Location:454582
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
    pfam13641
    Location:140365
    Glyco_tranf_2_3; Glycosyltransferase like family 2

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    171812656..173041559
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017008243.2XP_016863732.1  polypeptide N-acetylgalactosaminyltransferase-like 6 isoform X4

  2. XM_017008244.2XP_016863733.1  polypeptide N-acetylgalactosaminyltransferase-like 6 isoform X5

    Related
    ENSP00000423827.1, ENST00000508122.5
  3. XM_011531993.2XP_011530295.1  polypeptide N-acetylgalactosaminyltransferase-like 6 isoform X1

    See identical proteins and their annotated locations for XP_011530295.1

    Conserved Domains (4) summary
    cd02510
    Location:64359
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    cd00161
    Location:377505
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00652
    Location:375503
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
    pfam13641
    Location:61286
    Glyco_tranf_2_3; Glycosyltransferase like family 2
  4. XM_011531996.1XP_011530298.1  polypeptide N-acetylgalactosaminyltransferase-like 6 isoform X2

    See identical proteins and their annotated locations for XP_011530298.1

    Conserved Domains (3) summary
    cd02510
    Location:34288
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    cd00161
    Location:306434
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00652
    Location:304432
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
  5. XM_011531994.1XP_011530296.1  polypeptide N-acetylgalactosaminyltransferase-like 6 isoform X2

    See identical proteins and their annotated locations for XP_011530296.1

    Conserved Domains (3) summary
    cd02510
    Location:34288
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    cd00161
    Location:306434
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00652
    Location:304432
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
  6. XM_011531995.1XP_011530297.1  polypeptide N-acetylgalactosaminyltransferase-like 6 isoform X2

    See identical proteins and their annotated locations for XP_011530297.1

    Conserved Domains (3) summary
    cd02510
    Location:34288
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    cd00161
    Location:306434
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00652
    Location:304432
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
  7. XM_011531997.1XP_011530299.1  polypeptide N-acetylgalactosaminyltransferase-like 6 isoform X3

    Related
    ENSP00000483822.1, ENST00000616459.1
    Conserved Domains (3) summary
    cd02510
    Location:2255
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    cd00161
    Location:273401
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00652
    Location:271399
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
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