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OR2W5P olfactory receptor family 2 subfamily W member 5 pseudogene [ Homo sapiens (human) ]

Gene ID: 441932, updated on 25-Oct-2022

Summary

Official Symbol
OR2W5Pprovided by HGNC
Official Full Name
olfactory receptor family 2 subfamily W member 5 pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:15424
See related
Ensembl:ENSG00000290684 AllianceGenome:HGNC:15424
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR2W5; OST722
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene has a coding sequence that is comparable in length to other olfactory receptor genes, but it should be noted that a frameshift is present in the 3' coding region that disrupts the 7-transmembrane domain structure in the protein. It is unclear if the protein can function as an olfactory receptor or if an alternate function is served. For this reason, this gene has also been interpreted to be a pseudogene. [provided by RefSeq, Jan 2010]
Annotation information
Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
Orthologs
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Genomic context

See OR2W5P in Genome Data Viewer
Location:
1q44
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (247488093..247492409)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (246924900..246929217)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (247651395..247655711)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene NLR family pyrin domain containing 3 Neighboring gene uncharacterized LOC124904575 Neighboring gene olfactory receptor family 2 subfamily B member 11 Neighboring gene germinal center associated signaling and motility like Neighboring gene GCSAML antisense RNA 1 Neighboring gene olfactory receptor family 2 subfamily C member 3 Neighboring gene uncharacterized LOC102724446 Neighboring gene olfactory receptor family 2 subfamily G member 2

Genomic regions, transcripts, and products

General gene information

Homology

Other Names

  • olfactory receptor 2W5
  • olfactory receptor, family 2, subfamily W, member 5
  • putative olfactory receptor 2W5

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_169841.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL606804
    Related
    ENST00000641857.1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    247488093..247492409
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    246924900..246929217
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)