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PRAMEF25 PRAME family member 25 [ Homo sapiens (human) ]

Gene ID: 441873, updated on 19-Jul-2022

Summary

Official Symbol
PRAMEF25provided by HGNC
Official Full Name
PRAME family member 25provided by HGNC
Primary source
HGNC:HGNC:49179
See related
Ensembl:ENSG00000229571 AllianceGenome:HGNC:49179
Gene type
protein coding
RefSeq status
INFERRED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be involved in several processes, including negative regulation of apoptotic process; negative regulation of transcription, DNA-templated; and positive regulation of cell population proliferation. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

See PRAMEF25 in Genome Data Viewer
Location:
1p36.21
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (13070774..13077884)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (12668054..12672734, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene PRAME family member 27 Neighboring gene heterogeneous nuclear ribonucleoprotein C like 3 Neighboring gene PRAME family member 34, pseudogene Neighboring gene PRAME family member 35, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General protein information

Preferred Names
PRAME family member 25
Names
putative PRAME family member 25

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310134.3NP_001297063.1  PRAME family member 25

    See identical proteins and their annotated locations for NP_001297063.1

    Status: INFERRED

    Source sequence(s)
    AC245056
    Consensus CDS
    CCDS81265.1
    UniProtKB/Swiss-Prot
    A6NGN4
    Related
    ENSP00000478309.2, ENST00000619661.3

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    13070774..13077884
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_012132914.1 Reference GRCh38.p14 PATCHES

    Range
    225114..232224
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_015495298.1 Reference GRCh38.p14 PATCHES

    Range
    66390..73500
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187517.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    18527..23071
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017030184.2XP_016885673.2  PRAME family member 25 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    12668054..12672734 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047443644.1XP_047299600.1  PRAME family member 25 isoform X2