U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

FRG2B FSHD region gene 2 family member B [ Homo sapiens (human) ]

Gene ID: 441581, updated on 13-May-2022

Summary

Official Symbol
FRG2Bprovided by HGNC
Official Full Name
FSHD region gene 2 family member Bprovided by HGNC
Primary source
HGNC:HGNC:33518
See related
Ensembl:ENSG00000225899 AllianceGenome:HGNC:33518
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See FRG2B in Genome Data Viewer
Location:
10q26.3
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (133623895..133626795, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (134575320..134578220, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (135437399..135440299, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene synaptonemal complex central element protein 1 Neighboring gene shadow of prion protein pseudogene 1 Neighboring gene olfactory receptor family 6 subfamily L member 1 pseudogene Neighboring gene retinoic acid receptor responder 2 pseudogene 2 Neighboring gene angiogenic factor with G-patch and FHA domains 1 pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein FRG2-like-1
Names
FSHD region gene 2 protein family member B
HSA10-FRG2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080998.2NP_001074467.1  protein FRG2-like-1

    See identical proteins and their annotated locations for NP_001074467.1

    Status: VALIDATED

    Source sequence(s)
    AL731696, AY744466
    Consensus CDS
    CCDS44502.1
    UniProtKB/Swiss-Prot
    Q96QU4
    Related
    ENSP00000401310.1, ENST00000425520.2
    Conserved Domains (1) summary
    pfam15315
    Location:61241
    FRG2; Facioscapulohumeral muscular dystrophy candidate 2

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    133623895..133626795 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    134575320..134578220 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)