Format

Send to:

Choose Destination

CDNF cerebral dopamine neurotrophic factor [ Homo sapiens (human) ]

Gene ID: 441549, updated on 12-Sep-2021

Summary

Official Symbol
CDNFprovided by HGNC
Official Full Name
cerebral dopamine neurotrophic factorprovided by HGNC
Primary source
HGNC:HGNC:24913
See related
Ensembl:ENSG00000185267 MIM:611233
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ARMETL1
Expression
Broad expression in testis (RPKM 6.6), thyroid (RPKM 2.2) and 23 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See CDNF in Genome Data Viewer
Location:
10p13
Exon count:
4
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (14819245..14838073, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (14861244..14880036, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 107 member B Neighboring gene RNA, 5S ribosomal pseudogene 302 Neighboring gene ribosomal protein SA pseudogene 7 Neighboring gene zinc finger and SCAN domain containing 29 Neighboring gene heat shock protein family A (Hsp70) member 14 Neighboring gene SUV39H2 histone lysine methyltransferase Neighboring gene DNA cross-link repair 1C

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in dopaminergic neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
cerebral dopamine neurotrophic factor
Names
ARMET-like protein 1
arginine-rich, mutated in early stage tumors-like 1
conserved dopamine neurotrophic factor

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001029954.3NP_001025125.2  cerebral dopamine neurotrophic factor precursor

    See identical proteins and their annotated locations for NP_001025125.2

    Status: VALIDATED

    Source sequence(s)
    AC069544, AK131035, AV657190, BG213461, BQ025443, CN311321
    Consensus CDS
    CCDS31148.1
    UniProtKB/Swiss-Prot
    Q49AH0
    Related
    ENSP00000419395.1, ENST00000465530.2
    Conserved Domains (1) summary
    pfam10208
    Location:36180
    Armet; Degradation arginine-rich protein for mis-folding

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    14819245..14838073 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011519488.2XP_011517790.1  cerebral dopamine neurotrophic factor isoform X1

    Conserved Domains (1) summary
    pfam10208
    Location:36189
    Armet; Degradation arginine-rich protein for mis-folding
Support Center