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SMIM4 small integral membrane protein 4 [ Homo sapiens (human) ]

Gene ID: 440957, updated on 9-Jan-2022

Summary

Official Symbol
SMIM4provided by HGNC
Official Full Name
small integral membrane protein 4provided by HGNC
Primary source
HGNC:HGNC:37257
See related
Ensembl:ENSG00000168273
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C3orf78
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Ubiquitous expression in adrenal (RPKM 18.7), fat (RPKM 10.8) and 24 other tissues See more
Orthologs
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Genomic context

See SMIM4 in Genome Data Viewer
Location:
3p21.1
Exon count:
3
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (52535986..52541890)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (52570621..52575906)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene nischarin Neighboring gene stabilin 1 Neighboring gene 5'-nucleotidase domain containing 2 Neighboring gene RNA, U6 small nuclear 856, pseudogene Neighboring gene RNA, U6atac small nuclear 16, pseudogene Neighboring gene polybromo 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
small integral membrane protein 4
Names
UPF0640 protein C3orf78

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001124767.2NP_001118239.1  small integral membrane protein 4

    See identical proteins and their annotated locations for NP_001118239.1

    Status: VALIDATED

    Source sequence(s)
    AC112215, AK095910, BG031013, BM674004
    Consensus CDS
    CCDS46844.1
    UniProtKB/Swiss-Prot
    Q8WVI0
    Related
    ENSP00000417806.1, ENST00000477703.6
    Conserved Domains (1) summary
    pfam15114
    Location:368
    UPF0640; Uncharacterized protein family UPF0640

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    52535986..52541890
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011533729.2XP_011532031.1  small integral membrane protein 4 isoform X1

    Conserved Domains (1) summary
    pfam15114
    Location:93157
    UPF0640; uncharacterized protein family UPF0640

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_003192.1: Suppressed sequence

    Description
    NR_003192.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
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