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BCL2L15 BCL2 like 15 [ Homo sapiens (human) ]

Gene ID: 440603, updated on 5-Aug-2022

Summary

Official Symbol
BCL2L15provided by HGNC
Official Full Name
BCL2 like 15provided by HGNC
Primary source
HGNC:HGNC:33624
See related
Ensembl:ENSG00000188761 MIM:619660; AllianceGenome:HGNC:33624
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Bfk; C1orf178
Summary
Predicted to be involved in apoptotic process and regulation of apoptotic process. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in duodenum (RPKM 22.4), small intestine (RPKM 18.2) and 5 other tissues See more
Orthologs
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Genomic context

See BCL2L15 in Genome Data Viewer
Location:
1p13.2
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (113876816..113887581, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (113888477..113899246, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (114419438..114430203, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene round spermatid basic protein 1 Neighboring gene Sharpr-MPRA regulatory region 4295 Neighboring gene AP4B1 antisense RNA 1 Neighboring gene protein tyrosine phosphatase non-receptor type 22 Neighboring gene adaptor related protein complex 4 subunit beta 1 Neighboring gene GATA motif-containing MPRA enhancer 196 Neighboring gene DNA cross-link repair 1B

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ22588

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
bcl-2-like protein 15
Names
bcl-2 family kin
bcl2-L-15
pro-apoptotic Bcl-2 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001010922.3NP_001010922.1  bcl-2-like protein 15

    See identical proteins and their annotated locations for NP_001010922.1

    Status: VALIDATED

    Source sequence(s)
    AI821052, AL137856, AY265861, BX116361
    Consensus CDS
    CCDS30809.1
    UniProtKB/Swiss-Prot
    I6LA82, Q5TBC7
    UniProtKB/TrEMBL
    Q53EI7
    Related
    ENSP00000376992.3, ENST00000393316.8

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    113876816..113887581 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    113888477..113899246 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001029944.1: Suppressed sequence

    Description
    NM_001029944.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
  2. NM_001029945.1: Suppressed sequence

    Description
    NM_001029945.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
  3. NM_001029946.1: Suppressed sequence

    Description
    NM_001029946.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.