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Shc SHC-adaptor protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 44052, updated on 26-Aug-2021

Summary

Official Symbol
Shcprovided by FlyBase
Official Full Name
SHC-adaptor proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0015296
Locus tag
Dmel_CG3715
Gene type
protein coding
RNA name
SHC-adaptor protein
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG3715; D-Shc; Dmel\CG3715; dshc; dShc; DSHC; shc
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Genomic context

See Shc in Genome Data Viewer
Location:
67B5-67B5; 3-29 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (9427010..9428671)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (9420110..9421771)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene alpha-tubulin acetylase Neighboring gene uncharacterized protein Neighboring gene astray Neighboring gene ncRNA Neighboring gene Ribosomal protein S17 Neighboring gene Metal response element-binding Transcription Factor-1 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables epidermal growth factor receptor binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables receptor tyrosine kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in border follicle cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in compound eye photoreceptor cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in dorsal/ventral axis specification, ovarian follicular epithelium IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in epidermal growth factor receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in epidermal growth factor receptor signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in epidermal growth factor receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in epithelial cell migration, open tracheal system IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in fibroblast growth factor receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in imaginal disc-derived wing vein specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in melanotic encapsulation of foreign target IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mesodermal cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of TORC1 signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of dorsal/ventral axon guidance IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in torso signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in tracheal outgrowth, open tracheal system IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in transmembrane receptor protein tyrosine kinase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in vascular endothelial growth factor receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
SHC-adaptor protein
Names
CG3715-PA
SHC adaptor protein
Shc-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    9427010..9428671
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079944.3NP_524683.2  SHC-adaptor protein [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524683.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9V3C8
    Related
    FBpp0076186, FBtr0076458
    Conserved Domains (2) summary
    cd09925
    Location:293396
    SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
    cd01209
    Location:19178
    PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain
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