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ZNF724 zinc finger protein 724 [ Homo sapiens (human) ]

Gene ID: 440519, updated on 1-Jun-2020

Summary

Official Symbol
ZNF724provided by HGNC
Official Full Name
zinc finger protein 724provided by HGNC
Primary source
HGNC:HGNC:32460
See related
Ensembl:ENSG00000196081
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF724P
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See ZNF724 in Genome Data Viewer
Location:
19p12
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (23221584..23250456, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (23406607..23433172, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 730 Neighboring gene ribosomal protein L5 pseudogene Neighboring gene BCL2 interacting protein 3 pseudogene 37 Neighboring gene sorting nexin 6 pseudogene 1 Neighboring gene BCL2 interacting protein 3 pseudogene 38 Neighboring gene importin 5 pseudogene 1 Neighboring gene vomeronasal 1 receptor 90 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355404.2NP_001342333.1  zinc finger protein 724 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC092329
    Consensus CDS
    CCDS86737.1
    Related
    ENSP00000413411.1, ENST00000418100.5
    Conserved Domains (5) summary
    smart00349
    Location:464
    KRAB; krueppel associated box
    COG5048
    Location:143526
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:530610
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:340360
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:548572
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001355405.2NP_001342334.1  zinc finger protein 724 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC092329
    Conserved Domains (3) summary
    COG5048
    Location:79462
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:276296
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:484508
    zf-H2C2_2; Zinc-finger double domain
  3. NM_001355406.2NP_001342335.1  zinc finger protein 724 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC092329
    Conserved Domains (5) summary
    smart00349
    Location:258
    KRAB; krueppel associated box
    COG5048
    Location:137520
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:524604
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:334354
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:542566
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    23221584..23250456 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024451520.1XP_024307288.1  zinc finger protein 724 isoform X1

    Conserved Domains (3) summary
    COG5048
    Location:79462
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:276296
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:484508
    zf-H2C2_2; Zinc-finger double domain
  2. XM_024451521.1XP_024307289.1  zinc finger protein 724 isoform X2

    Related
    ENSP00000471547.1, ENST00000597037.1
    Conserved Domains (1) summary
    smart00349
    Location:464
    KRAB; krueppel associated box

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_005791.3: Suppressed sequence

    Description
    NG_005791.3: This RefSeq was permanently suppressed because it is now thought that this gene is a transcribed pseudogene.
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