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HSBP1L1 heat shock factor binding protein 1 like 1 [ Homo sapiens (human) ]

Gene ID: 440498, updated on 23-Nov-2021

Summary

Official Symbol
HSBP1L1provided by HGNC
Official Full Name
heat shock factor binding protein 1 like 1provided by HGNC
Primary source
HGNC:HGNC:37243
See related
Ensembl:ENSG00000226742
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in colon (RPKM 10.7), kidney (RPKM 8.1) and 25 other tissues See more
Orthologs
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Genomic context

See HSBP1L1 in Genome Data Viewer
Location:
18q23
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 18 NC_000018.10 (79964643..79970822)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (77724643..77730822)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene potassium voltage-gated channel modifier subfamily G member 2 Neighboring gene Sharpr-MPRA regulatory region 1017 Neighboring gene solute carrier family 66 member 2 Neighboring gene thioredoxin like 4A Neighboring gene Sharpr-MPRA regulatory region 15651 Neighboring gene ribosome binding factor A

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10967, MGC189743

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cellular heat acclimation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in negative regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
heat shock factor-binding protein 1-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001136180.2NP_001129652.1  heat shock factor-binding protein 1-like protein 1

    See identical proteins and their annotated locations for NP_001129652.1

    Status: VALIDATED

    Source sequence(s)
    AC114341, BC040056, BC157848, CA444419, DA919112
    Consensus CDS
    CCDS45886.1
    UniProtKB/Swiss-Prot
    C9JCN9
    Related
    ENSP00000414236.1, ENST00000451882.3
    Conserved Domains (1) summary
    pfam06825
    Location:1462
    HSBP1; Heat shock factor binding protein 1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p13 Primary Assembly

    Range
    79964643..79970822
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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