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NPIPB15 nuclear pore complex interacting protein family member B15 [ Homo sapiens (human) ]

Gene ID: 440348, updated on 10-Oct-2023

Summary

Official Symbol
NPIPB15provided by HGNC
Official Full Name
nuclear pore complex interacting protein family member B15provided by HGNC
Primary source
HGNC:HGNC:34409
See related
Ensembl:ENSG00000196436 AllianceGenome:HGNC:34409
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NPIPL2; A-761H5.4
Summary
Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis (RPKM 17.7), skin (RPKM 3.0) and 23 other tissues See more
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Genomic context

See NPIPB15 in Genome Data Viewer
Location:
16q23.1
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (74376306..74392115)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (80194084..80209885)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (74410204..74426013)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene ribosomal protein L21 pseudogene 118 Neighboring gene prostate cancer associated HIP1 interacting lncRNA Neighboring gene pyruvate dehydrogenase phosphatase regulatory subunit 2, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:74390671-74391172 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:74402112-74402363 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11107 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:74414879-74415096 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:74431311-74432152 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:74433981-74434480 Neighboring gene uncharacterized LOC105376772 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:74441122-74442022 Neighboring gene C-type lectin domain family 18 member B Neighboring gene uncharacterized LOC107984827

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
nuclear pore complex-interacting protein family member B15
Names
nuclear pore complex interacting protein-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001306094.2NP_001293023.1  nuclear pore complex-interacting protein family member B15 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001293023.1

    Status: VALIDATED

    Source sequence(s)
    AC009053
    Consensus CDS
    CCDS76897.1
    UniProtKB/Swiss-Prot
    A6NHN6, C9J9U8
    UniProtKB/TrEMBL
    I3L0I5
    Related
    ENSP00000508772.1, ENST00000692376.1
    Conserved Domains (1) summary
    pfam06409
    Location:23299
    NPIP; Nuclear pore complex interacting protein (NPIP)
  2. NM_001385737.1NP_001372666.1  nuclear pore complex-interacting protein family member B15 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC009053
    UniProtKB/TrEMBL
    I3L0I5
    Conserved Domains (1) summary
    pfam06409
    Location:37306
    NPIP; Nuclear pore complex interacting protein (NPIP)
  3. NM_001385738.1NP_001372667.1  nuclear pore complex-interacting protein family member B15 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC009053
    UniProtKB/TrEMBL
    O75199
    Conserved Domains (1) summary
    pfam06409
    Location:12177
    NPIP; Nuclear pore complex interacting protein (NPIP)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    74376306..74392115
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047434161.1XP_047290117.1  nuclear pore complex-interacting protein family member B15 isoform X1

    UniProtKB/TrEMBL
    I3L0I5
  2. XM_017023248.1XP_016878737.1  nuclear pore complex-interacting protein family member B15 isoform X2

    UniProtKB/Swiss-Prot
    A6NHN6, C9J9U8
    UniProtKB/TrEMBL
    I3L0I5
    Related
    ENSP00000411140.1, ENST00000429990.1
    Conserved Domains (1) summary
    pfam06409
    Location:23299
    NPIP; Nuclear pore complex interacting protein (NPIP)
  3. XM_047434162.1XP_047290118.1  nuclear pore complex-interacting protein family member B15 isoform X3

    UniProtKB/TrEMBL
    O75199
  4. XM_047434164.1XP_047290120.1  nuclear pore complex-interacting protein family member B15 isoform X6

  5. XM_024450290.1XP_024306058.1  nuclear pore complex-interacting protein family member B15 isoform X4

    UniProtKB/TrEMBL
    O75199
    Conserved Domains (1) summary
    pfam06409
    Location:23160
    NPIP; Nuclear pore complex interacting protein (NPIP)
  6. XM_047434163.1XP_047290119.1  nuclear pore complex-interacting protein family member B15 isoform X5

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    80194084..80209885
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054380384.1XP_054236359.1  nuclear pore complex-interacting protein family member B15 isoform X2

    UniProtKB/Swiss-Prot
    A6NHN6, C9J9U8
    UniProtKB/TrEMBL
    I3L0I5
  2. XM_054380385.1XP_054236360.1  nuclear pore complex-interacting protein family member B15 isoform X4

    UniProtKB/TrEMBL
    O75199
  3. XM_054380386.1XP_054236361.1  nuclear pore complex-interacting protein family member B15 isoform X7

  4. XM_054380387.1XP_054236362.1  nuclear pore complex-interacting protein family member B15 isoform X6

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001018059.2: Suppressed sequence

    Description
    NM_001018059.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.