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GOLGA8B golgin A8 family member B [ Homo sapiens (human) ]

Gene ID: 440270, updated on 11-Jun-2021

Summary

Official Symbol
GOLGA8Bprovided by HGNC
Official Full Name
golgin A8 family member Bprovided by HGNC
Primary source
HGNC:HGNC:31973
See related
Ensembl:ENSG00000215252 MIM:609619
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GOLGA5
Expression
Ubiquitous expression in thyroid (RPKM 78.1), testis (RPKM 47.6) and 24 other tissues See more
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Genomic context

See GOLGA8B in Genome Data Viewer
Location:
15q14
Exon count:
24
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (34525095..34583651, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (34817296..34875852, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene fascin actin-bundling protein 1 pseudogene 1 Neighboring gene dynamin 1 pseudogene 5 Neighboring gene microRNA 1233-2 Neighboring gene amyloid beta precursor protein binding family A member 2 pseudogene Neighboring gene Sharpr-MPRA regulatory region 9988 Neighboring gene Sharpr-MPRA regulatory region 12620

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • KIAA0855

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in spindle assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
 
is_active_in Golgi cis cisterna IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in Golgi cisterna membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cis-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
golgin subfamily A member 8B
Names
golgi autoantigen, golgin subfamily a, 8B
golgin-67

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001023567.5NP_001018861.3  golgin subfamily A member 8B

    See identical proteins and their annotated locations for NP_001018861.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript and encodes the functional protein.
    Source sequence(s)
    AC027139
    Consensus CDS
    CCDS45211.1
    UniProtKB/Swiss-Prot
    A8MQT2
    Related
    ENSP00000507830.1, ENST00000683415.1
    Conserved Domains (2) summary
    pfam01496
    Location:268322
    V_ATPase_I; V-type ATPase 116kDa subunit family
    pfam15070
    Location:218593
    GOLGA2L5; Putative golgin subfamily A member 2-like protein 5

RNA

  1. NR_027410.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents use of an alternate upstream promoter and additional 5' exons and retains an intron, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC027139
    Related
    ENST00000569100.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    34525095..34583651 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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