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MZT1 mitotic spindle organizing protein 1 [ Homo sapiens (human) ]

Gene ID: 440145, updated on 4-Oct-2020

Summary

Official Symbol
MZT1provided by HGNC
Official Full Name
mitotic spindle organizing protein 1provided by HGNC
Primary source
HGNC:HGNC:33830
See related
Ensembl:ENSG00000204899 MIM:613448
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MOZART1; C13orf37
Expression
Ubiquitous expression in brain (RPKM 11.3), bone marrow (RPKM 9.3) and 25 other tissues See more
Orthologs

Genomic context

See MZT1 in Genome Data Viewer
Location:
13q21.33
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 13 NC_000013.11 (72708367..72727629, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (73282495..73301938, complement)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene ribosomal protein L21 pseudogene 110 Neighboring gene RNA, U6 small nuclear 80, pseudogene Neighboring gene BORA aurora kinase A activator Neighboring gene DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease Neighboring gene progesterone immunomodulatory binding factor 1 Neighboring gene RNA, U6 small nuclear 79, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Genome-wide association study of obsessive-compulsive disorder.
GeneReviews: Not available

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ21869, MGC150539

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
gamma-tubulin complex localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
microtubule nucleation by interphase microtubule organizing center IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitotic spindle assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
centrosome IDA
Inferred from Direct Assay
more info
PubMed 
cytosol TAS
Traceable Author Statement
more info
 
gamma-tubulin ring complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
gamma-tubulin ring complex IDA
Inferred from Direct Assay
more info
PubMed 
interphase microtubule organizing center IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spindle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spindle IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
mitotic-spindle organizing protein 1
Names
mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001071775.3NP_001065243.1  mitotic-spindle organizing protein 1

    See identical proteins and their annotated locations for NP_001065243.1

    Status: VALIDATED

    Source sequence(s)
    AK025522, AL356754, BC125183
    Consensus CDS
    CCDS31990.1
    UniProtKB/Swiss-Prot
    Q08AG7
    Related
    ENSP00000367049.3, ENST00000377818.4
    Conserved Domains (1) summary
    pfam12554
    Location:2268
    MOZART1; Mitotic-spindle organizing gamma-tubulin ring associated

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p13 Primary Assembly

    Range
    72708367..72727629 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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