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DBX2 developing brain homeobox 2 [ Homo sapiens (human) ]

Gene ID: 440097, updated on 11-Jun-2021

Summary

Official Symbol
DBX2provided by HGNC
Official Full Name
developing brain homeobox 2provided by HGNC
Primary source
HGNC:HGNC:33186
See related
Ensembl:ENSG00000185610
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in brain (RPKM 1.7), testis (RPKM 0.5) and 2 other tissues See more
Orthologs
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Genomic context

See DBX2 in Genome Data Viewer
Location:
12q12
Exon count:
4
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (45014672..45051099, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (45408455..45444882, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene transmembrane protein 117 Neighboring gene IQ motif containing F1 pseudogene Neighboring gene neural EGFL like 2 Neighboring gene uncharacterized LOC105369742 Neighboring gene Rac GTPase activating protein 1 pseudogene 1 Neighboring gene small RNA binding exonuclease protection factor La like 3, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ16139

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific ISA
Inferred from Sequence Alignment
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in chromatin ISA
Inferred from Sequence Alignment
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
homeobox protein DBX2
Names
developing brain homeobox protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004329.3NP_001004329.2  homeobox protein DBX2

    See identical proteins and their annotated locations for NP_001004329.2

    Status: VALIDATED

    Source sequence(s)
    AC079033, AC089986, AK131230
    Consensus CDS
    CCDS31781.1
    UniProtKB/Swiss-Prot
    Q6ZNG2
    Related
    ENSP00000331470.6, ENST00000332700.6
    Conserved Domains (1) summary
    pfam00046
    Location:189242
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    45014672..45051099 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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