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ORF1ab ORF1a polyprotein;ORF1ab polyprotein [ Severe acute respiratory syndrome coronavirus 2 ]

Gene ID: 43740578, updated on 31-Mar-2020

Summary

Gene symbol
ORF1ab
Gene description
ORF1a polyprotein;ORF1ab polyprotein
Locus tag
GU280_gp01
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Severe acute respiratory syndrome coronavirus 2 (isolate: Wuhan-Hu-1, nat-host: Homo sapiens)
Lineage
Viruses; Riboviria; Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae; Betacoronavirus; Sarbecovirus

Genomic context

Sequence:
NC_045512.2 (266..21555)

NC_045512.2Genomic Context describing neighboring genes Neighboring gene surface glycoprotein Neighboring gene ORF3a protein

General gene information

stem_loop

  • Loc: 13476-13503 function = Coronavirus frameshifting stimulation element stem-loop 1 , inference = COORDINATES: profile:Rfam-release-14.1:RF00507,Infernal:1.1.2
  • Loc: 13488-13542 function = Coronavirus frameshifting stimulation element stem-loop 2 , inference = COORDINATES: profile:profile:Rfam-release-14.1:RF00507,Infernal:1.1.2

General protein information

Preferred Names
ORF1a polyprotein;ORF1ab polyprotein
Names
leader protein
nsp2
nsp3
nsp4
3C-like proteinase
nsp6
nsp7
nsp8
nsp9
nsp10
RNA-dependent RNA polymerase
helicase
3'-to-5' exonuclease
endoRNAse
2'-O-ribose methyltransferase
leader protein
nsp2
nsp3
nsp4
3C-like proteinase
nsp6
nsp7
nsp8
nsp9
nsp10
nsp11
YP_009724389.1
  • pp1ab; translated by -1 ribosomal frameshift
YP_009725295.1
  • pp1a

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_045512.2 Reference assembly

    Range
    266..21555
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_009724389.1 orf1ab polyprotein [Severe acute respiratory syndrome coronavirus 2]

    Status: PROVISIONAL

  2. YP_009725297.1 leader protein

  3. YP_009725298.1 nsp2

  4. YP_009725299.1 nsp3

  5. YP_009725300.1 nsp4

  6. YP_009725301.1 3C-like proteinase

  7. YP_009725302.1 nsp6

  8. YP_009725303.1 nsp7

  9. YP_009725304.1 nsp8

  10. YP_009725305.1 nsp9

  11. YP_009725306.1 nsp10

  12. YP_009725307.1 RNA-dependent RNA polymerase

  13. YP_009725308.1 helicase

  14. YP_009725309.1 3'-to-5' exonuclease

  15. YP_009725310.1 endoRNAse

  16. YP_009725311.1 2'-O-ribose methyltransferase

  17. YP_009725295.1 orf1a polyprotein [Severe acute respiratory syndrome coronavirus 2]

    Status: PROVISIONAL

  18. YP_009742608.1 leader protein

  19. YP_009742609.1 nsp2

  20. YP_009742610.1 nsp3

  21. YP_009742611.1 nsp4

  22. YP_009742612.1 3C-like proteinase

  23. YP_009742613.1 nsp6

  24. YP_009742614.1 nsp7

  25. YP_009742615.1 nsp8

  26. YP_009742616.1 nsp9

  27. YP_009742617.1 nsp10

  28. YP_009725312.1 nsp11

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