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N nucleocapsid phosphoprotein [ Severe acute respiratory syndrome coronavirus 2 ]

Gene ID: 43740575, updated on 11-Sep-2021

Summary

Gene symbol
N
Gene description
nucleocapsid phosphoprotein
Locus tag
GU280_gp10
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Severe acute respiratory syndrome coronavirus 2 (isolate: Wuhan-Hu-1, nat-host: Homo sapiens)
Lineage
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae; Betacoronavirus; Sarbecovirus
Summary
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The nucleocapsid phosphoprotein is a structural protein that binds to, protects the viral RNA genome and is involved in packaging the RNA into virus particles. The N protein has been suggested as an antiviral drug target.
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Genomic context

Sequence:
NC_045512.2 (28274..29533)

NC_045512.2Genomic Context describing neighboring genes Neighboring gene ORF7a protein Neighboring gene ORF7b Neighboring gene ORF8 protein Neighboring gene ORF10 protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
nucleocapsid phosphoprotein
YP_009724397.2
  • ORF9; structural protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_045512.2 Reference assembly

    Range
    28274..29533
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_009724397.2 nucleocapsid phosphoprotein [Severe acute respiratory syndrome coronavirus 2]

    Status: PROVISIONAL

    Conserved Domains (1) summary
    pfam00937
    Location:40388
    Corona_nucleoca; Coronavirus nucleocapsid protein
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