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ORF7a ORF7a protein [ Severe acute respiratory syndrome coronavirus 2 ]

Gene ID: 43740573, updated on 9-May-2021

Summary

Gene symbol
ORF7a
Gene description
ORF7a protein
Locus tag
GU280_gp07
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Severe acute respiratory syndrome coronavirus 2 (isolate: Wuhan-Hu-1, nat-host: Homo sapiens)
Lineage
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae; Betacoronavirus; Sarbecovirus
Summary
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ ORF7a encodes a viral accessory protein. Based on its similarity to other coronavirus proteins, ORF7a protein is thought to be a type I transmembrane protein.
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Genomic context

Sequence:
NC_045512.2 (27394..27759)

NC_045512.2Genomic Context describing neighboring genes Neighboring gene membrane glycoprotein Neighboring gene ORF6 protein Neighboring gene ORF7b Neighboring gene ORF8 protein Neighboring gene nucleocapsid phosphoprotein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_045512.2 Reference assembly

    Range
    27394..27759
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_009724395.1 ORF7a protein [Severe acute respiratory syndrome coronavirus 2]

    Status: PROVISIONAL

    Conserved Domains (1) summary
    cd21684
    Location:1121
    ORF7a_SARS-CoV-2-like; Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) structural accessory protein ORF7a and a bat coronavirus (BatCoV RaTG13) from related betacoronaviruses in the subgenera Sarbecovirus (B lineage)
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