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ORF6 ORF6 protein [ Severe acute respiratory syndrome coronavirus 2 ]

Gene ID: 43740572, updated on 9-May-2021

Summary

Gene symbol
ORF6
Gene description
ORF6 protein
Locus tag
GU280_gp06
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Severe acute respiratory syndrome coronavirus 2 (isolate: Wuhan-Hu-1, nat-host: Homo sapiens)
Lineage
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae; Betacoronavirus; Sarbecovirus
Summary
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ ORF6 encodes a viral accessory protein. Based on its similarity to other coronavirus proteins, ORF6 protein is thought to play a role in viral pathogenesis.
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Genomic context

Sequence:
NC_045512.2 (27202..27387)

NC_045512.2Genomic Context describing neighboring genes Neighboring gene envelope protein Neighboring gene membrane glycoprotein Neighboring gene ORF7a protein Neighboring gene ORF7b Neighboring gene ORF8 protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_045512.2 Reference assembly

    Range
    27202..27387
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_009724394.1 ORF6 protein [Severe acute respiratory syndrome coronavirus 2]

    Status: PROVISIONAL

    Conserved Domains (1) summary
    pfam12133
    Location:161
    Sars6; Open reading frame 6 from SARS coronavirus
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