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ada adenosine deaminase [ Danio rerio (zebrafish) ]

Gene ID: 436919, updated on 11-Nov-2018

Summary

Official Symbol
adaprovided by ZNC
Official Full Name
adenosine deaminaseprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040718-393
See related
Ensembl:ENSDARG00000003113 Vega:OTTDARG00000030502
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
zgc:92028
Orthologs

Genomic context

See ada in Genome Data Viewer
Location:
chromosome: 23
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (25946448..25976656, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (26019907..26050115, complement)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene tocopherol (alpha) transfer protein-like Neighboring gene protein kinase (cAMP-dependent, catalytic) inhibitor gamma Neighboring gene si:dkey-78k11.9 Neighboring gene cellular communication network factor 5

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
adenosine deaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
adenosine deaminase activity IDA
Inferred from Direct Assay
more info
PubMed 
adenosine deaminase activity IEA
Inferred from Electronic Annotation
more info
 
adenosine deaminase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
deaminase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
zinc ion binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
adenosine catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
adenosine catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
hypoxanthine salvage IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
inosine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
inosine biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 
nucleotide metabolic process IEA
Inferred from Electronic Annotation
more info
 
purine ribonucleoside monophosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell junction IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic vesicle lumen IEA
Inferred from Electronic Annotation
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
lysosome IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
adenosine deaminase
Names
ada1
adenosine aminohydrolase
NP_001002646.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002646.1NP_001002646.1  adenosine deaminase

    See identical proteins and their annotated locations for NP_001002646.1

    Status: PROVISIONAL

    Source sequence(s)
    BC076532
    UniProtKB/Swiss-Prot
    Q6DG22
    Related
    ENSDARP00000005284.7, OTTDARP00000033623, ENSDART00000019519.8, OTTDART00000042254
    Conserved Domains (1) summary
    cd01320
    Location:11350
    ADA; Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    25946448..25976656 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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