polr3h polymerase (RNA) III (DNA directed) polypeptide H [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: polr3hprovided by ZNC
Official Full Name: polymerase (RNA) III (DNA directed) polypeptide Hprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-179
See related: Ensembl:ENSDARG00000102590 AllianceGenome:ZFIN:ZDB-GENE-040718-179
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92878
Summary: Predicted to enable DNA binding activity and DNA-directed 5'-3' RNA polymerase activity. Acts upstream of or within hematopoietic stem cell homeostasis. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Is expressed in hematopoietic system. Orthologous to human POLR3H (RNA polymerase III subunit H). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (5019502..5030089, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (5109661..5120248, complement)
103	previous assembly	Zv9 (GCF_000002035.4)	3	NC_007114.5 (5689032..5699669)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-directed 5'-3' RNA polymerase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA-templated transcription	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within DNA-templated transcription initiation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within hematopoietic stem cell homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transcription initiation at RNA polymerase III promoter	IBA Inferred from Biological aspect of Ancestor more info	PubMed

Component	Evidence Code	Pubs
part_of DNA-directed RNA polymerase complex	IEA Inferred from Electronic Annotation more info
part_of RNA polymerase III complex	IBA Inferred from Biological aspect of Ancestor more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: DNA-directed RNA polymerase III subunit RPC8

NP_001002476.1

EC 2.7.7.6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002476.1 → NP_001002476.1 DNA-directed RNA polymerase III subunit RPC8

See identical proteins and their annotated locations for NP_001002476.1

Status: PROVISIONAL

Source sequence(s)

BC076336

UniProtKB/TrEMBL

Q6DGK6

Related

ENSDARP00000138726.1, ENSDART00000167153.2

Conserved Domains (3) summary

COG1095
Location:1 → 212

RPB7; DNA-directed RNA polymerase, subunit E'/Rpb7 [Transcription]

cd04330
Location:2 → 81

RNAP_III_Rpc25_N; RNAP_III_Rpc25_N: Rpc25, N-terminal ribonucleoprotein (RNP) domain. Rpc25 is a subunit of eukaryotic RNA polymerase (RNAP) III and is homologous to Rpa43 of eukaryotic RNAP I, Rpb7 of eukaryotic RNAP II, and RpoE of archaeal RNAP. Rpc25 has two domains, ...

pfam08292
Location:79 → 212

RNA_pol_Rbc25; RNA polymerase III subunit Rpc25