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5-HT7 5-hydroxytryptamine (serotonin) receptor 7 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43669, updated on 9-Oct-2018

Summary

Official Symbol
5-HT7provided by FlyBase
Official Full Name
5-hydroxytryptamine (serotonin) receptor 7provided by FlyBase
Primary source
FLYBASE:FBgn0004573
Locus tag
Dmel_CG12073
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
5-HT-dro; 5-HT-dro1; 5-HT7Dro; 5-HTdro1; 5-HT[7]Dro; 5-HT[[7Dro]]; 5-HT[[7]]; 5-HT[[7]]Dro; 5-HT[[dro1]]; 5HT-7; 5HT-dro; 5HT-dro1; 5HT-R1; 5HT7; 5htdror; 5HT[[7Dro]]; CG12073; Dm5-HT[[7]]; Dm5HTdro1; Dmel\CG12073; DRO1; HT7

Genomic context

See 5-HT7 in Genome Data Viewer
Location:
100B1-100B1; 3-102 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30968236..31016875, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (26793958..26842597, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Copper transporter 1C Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene Calcineurin A1 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Homology

  • Homologs of the 5-HT7 gene: The 5-HT7 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, and frog.

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
G protein-coupled amine receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled serotonin receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled serotonin receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
G protein-coupled serotonin receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
G protein-coupled serotonin receptor activity TAS
Traceable Author Statement
more info
PubMed 
neurotransmitter receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
dendrite IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
5-hydroxytryptamine (serotonin) receptor 7
Names
5-HT7-PA
5-HT7-PB
CG12073-PA
CG12073-PB
serotonin receptor
serotonin receptor 1
serotonin receptor 7

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    30968236..31016875 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001276202.1NP_001263131.1  5-hydroxytryptamine (serotonin) receptor 7, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001263131.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P20905
    UniProtKB/TrEMBL
    A0A0B4KHG3
    Related
    FBpp0306575, FBtr0334508
    Conserved Domains (2) summary
    pfam00001
    Location:179507
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:173342
    7tm_4; Olfactory receptor
  2. NM_079860.3NP_524599.1  5-hydroxytryptamine (serotonin) receptor 7, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524599.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P20905
    UniProtKB/TrEMBL
    A0A0B4KHG3
    Related
    FBpp0085108, FBtr0085746
    Conserved Domains (2) summary
    pfam00001
    Location:179507
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:173342
    7tm_4; Olfactory receptor
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