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Foxr2 forkhead box R2 [ Mus musculus (house mouse) ]

Gene ID: 436240, updated on 26-Sep-2022

Summary

Official Symbol
Foxr2provided by MGI
Official Full Name
forkhead box R2provided by MGI
Primary source
MGI:MGI:3511682
See related
Ensembl:ENSMUSG00000071665 AllianceGenome:MGI:3511682
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Foxn6; EG436240
Summary
Predicted to enable sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human FOXR2 (forkhead box R2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See Foxr2 in Genome Data Viewer
Location:
X; X F3
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (151897577..151915857)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (153114581..153132861)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 9530051G07 gene Neighboring gene predicted pseudogene 5396 Neighboring gene Ras-related GTP binding B Neighboring gene Kruppel-like factor 8

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables sequence-specific double-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
forkhead box protein R2
Names
forkhead box protein N6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034894.3NP_001030066.1  forkhead box protein R2

    See identical proteins and their annotated locations for NP_001030066.1

    Status: VALIDATED

    Source sequence(s)
    AL672293
    Consensus CDS
    CCDS30479.1
    UniProtKB/Swiss-Prot
    B2RXE0, Q3UM89
    Related
    ENSMUSP00000093984.4, ENSMUST00000096265.10
    Conserved Domains (1) summary
    pfam00250
    Location:182272
    Forkhead; Forkhead domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    151897577..151915857
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011247841.1XP_011246143.1  forkhead box protein R2 isoform X1

    See identical proteins and their annotated locations for XP_011246143.1

    UniProtKB/Swiss-Prot
    B2RXE0, Q3UM89
    Conserved Domains (1) summary
    pfam00250
    Location:182272
    Forkhead; Forkhead domain
  2. XM_017318543.2XP_017174032.1  forkhead box protein R2 isoform X1

    UniProtKB/Swiss-Prot
    B2RXE0, Q3UM89
    Conserved Domains (1) summary
    pfam00250
    Location:182272
    Forkhead; Forkhead domain