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Dupd1 dual specificity phosphatase and pro isomerase domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 435391, updated on 22-May-2018

Summary

Official Symbol
Dupd1provided by MGI
Official Full Name
dual specificity phosphatase and pro isomerase domain containing 1provided by MGI
Primary source
MGI:MGI:3647127
See related
Ensembl:ENSMUSG00000063821
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EG435391
Expression
Biased expression in testis adult (RPKM 1.7), mammary gland adult (RPKM 0.7) and 5 other tissues See more
Orthologs

Genomic context

See Dupd1 in Genome Data Viewer
Location:
14; 14 A3
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (21676212..21714576, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (22495794..22533798, complement)

Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 30363 Neighboring gene K(lysine) acetyltransferase 6B Neighboring gene dual specificity phosphatase 13 Neighboring gene sterile alpha motif domain containing 8

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
protein tyrosine/serine/threonine phosphatase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein dephosphorylation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
protein-containing complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
dual specificity phosphatase DUPD1
NP_001013848.1
XP_006519280.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013826.2NP_001013848.1  dual specificity phosphatase DUPD1

    See identical proteins and their annotated locations for NP_001013848.1

    Status: PROVISIONAL

    Source sequence(s)
    AK075665
    Consensus CDS
    CCDS26863.1
    UniProtKB/Swiss-Prot
    Q8BK84
    Related
    ENSMUSP00000073534.5, ENSMUST00000073870.6
    Conserved Domains (1) summary
    cd00127
    Location:53196
    DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

    Range
    21676212..21714576 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006519217.3XP_006519280.1  dual specificity phosphatase DUPD1 isoform X1

    See identical proteins and their annotated locations for XP_006519280.1

    UniProtKB/Swiss-Prot
    Q8BK84
    Conserved Domains (1) summary
    cd00127
    Location:53196
    DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
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