Atp6ap1l ATPase, H+ transporting, lysosomal accessory protein 1-like [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Atp6ap1lprovided by MGI
Official Full Name: ATPase, H+ transporting, lysosomal accessory protein 1-likeprovided by MGI
Primary source: MGI:MGI:3648665
See related: Ensembl:ENSMUSG00000078958 AllianceGenome:MGI:3648665
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: EG435376
Summary: Predicted to be involved in regulation of cellular pH. Predicted to be part of plasma membrane proton-transporting V-type ATPase complex. Orthologous to human ATP6AP1L (ATPase H+ transporting accessory protein 1 like (pseudogene)). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in testis adult (RPKM 39.9), frontal lobe adult (RPKM 6.1) and 1 other tissue See more
Orthologs: human all
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Genomic context

Location:: 13; 13 C3

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	13	NC_000079.7 (91031558..91053478, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	13	NC_000079.6 (90883439..90905355, complement)

Chromosome 13 - NC_000079.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

Homologs of the Atp6ap1l gene: The Atp6ap1l gene is conserved in dog, cow, rat, zebrafish, and frog.
Orthologs from Annotation Pipeline: 236 organisms have orthologs with human gene Atp6ap1l
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in regulation of cellular pH	IBA Inferred from Biological aspect of Ancestor more info	PubMed

Component	Evidence Code	Pubs
part_of proton-transporting V-type ATPase complex	IBA Inferred from Biological aspect of Ancestor more info	PubMed

General protein information

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Preferred Names: V-type proton ATPase subunit S1-like protein

Names: Ac45-related protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001145879.1 → NP_001139351.1 V-type proton ATPase subunit S1-like protein precursor

Status: VALIDATED

Source sequence(s)

AC108947, CJ050414, CX238982

Consensus CDS

CCDS49325.1

UniProtKB/TrEMBL

D3Z5W0

Related

ENSMUSP00000105168.3, ENSMUST00000109541.4

Conserved Domains (1) summary

pfam01299
Location:123 → 277

Lamp; Lysosome-associated membrane glycoprotein (Lamp)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000079.7 Reference GRCm39 C57BL/6J

Range

91031558..91053478 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006517291.2 → XP_006517354.1 V-type proton ATPase subunit S1-like protein isoform X2

Conserved Domains (1) summary

pfam05827
Location:46 → 186

ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)
XM_006517290.4 → XP_006517353.1 V-type proton ATPase subunit S1-like protein isoform X1

Conserved Domains (1) summary

pfam05827
Location:90 → 230

ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)
XM_036158087.1 → XP_036013980.1 V-type proton ATPase subunit S1-like protein isoform X3

Conserved Domains (1) summary

pfam05827
Location:34 → 174

ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)
XM_036158088.1 → XP_036013981.1 V-type proton ATPase subunit S1-like protein isoform X3

Conserved Domains (1) summary

pfam05827
Location:34 → 174

ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)
XM_017315542.3 → XP_017171031.1 V-type proton ATPase subunit S1-like protein isoform X1

Conserved Domains (1) summary

pfam05827
Location:90 → 230

ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)