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CG7601 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43502, updated on 11-Apr-2024

Summary

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Official Symbol
CG7601provided by FlyBase
Primary source
FLYBASE:FBgn0027583
Locus tag
Dmel_CG7601
See related
AllianceGenome:FB:FBgn0027583
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:GH06026; DHRS7B; Dmel\CG7601
Summary
Predicted to enable NAD-retinol dehydrogenase activity. Is expressed in adult head. Orthologous to several human genes including DHRS7B (dehydrogenase/reductase 7B). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
99B9-99B9; 3-99 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29735269..29736745, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25560991..25562467, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene pterin-4a-carbinolamine dehydratase Neighboring gene N(alpha)-acetyltransferase 40 Neighboring gene uncharacterized protein Neighboring gene Kuzbanian-like Neighboring gene Complex I intermediate-associated protein, 30 kDa Neighboring gene Glucosamine-phosphate N-acetyltransferase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of two pathways mediating protein targeting from ER to lipid droplets. Song J, et al. Nat Cell Biol, 2022 Sep. PMID 36050470, Free PMC Article
  2. Drosophila glia: Few cell types and many conserved functions. Yildirim K, et al. Glia, 2019 Jan. PMID 30443934
  3. Mass Spectrometry-Based Screening Platform Reveals Orco Interactome in Drosophila melanogaster. Yu KE, et al. Mol Cells, 2018 Feb 28. PMID 29429152, Free PMC Article
  4. siRNA screen identifies QPCT as a druggable target for Huntington's disease. Jimenez-Sanchez M, et al. Nat Chem Biol, 2015 May. PMID 25848931, Free PMC Article
  5. Latitudinal clines in gene expression and cis-regulatory element variation in Drosophila melanogaster. Juneja P, et al. BMC Genomics, 2016 Nov 28. PMID 27894253, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables all-trans-retinol dehydrogenase (NAD+) activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7601-PA
NP_651717.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    29735269..29736745 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143460.4 → NP_651717.1  uncharacterized protein Dmel_CG7601 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651717.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9Y140
    Related
    FBpp0084910
    Conserved Domains (2) summary
    cd05332
    Location:51 → 310
    11beta-HSD1_like_SDR_c; 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs
    PRK06181
    Location:53 → 314
    PRK06181; short chain dehydrogenase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9Y140.1 Q9Y140

Gene LinkOut

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