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dmrt99B doublesex-Mab related 99B [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43495, updated on 5-Jan-2023

Summary

Official Symbol
dmrt99Bprovided by FlyBase
Official Full Name
doublesex-Mab related 99Bprovided by FlyBase
Primary source
FLYBASE:FBgn0039683
Locus tag
Dmel_CG15504
See related
AllianceGenome:FB:FBgn0039683
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG15504; Dmel\CG15504
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and sex differentiation. Predicted to be active in nucleus. Is expressed in VUM motor neurons; anterior ectoderm derivative; presumptive embryonic/larval system; and ventral midline of embryo. Orthologous to several human genes including DMRTA2 (DMRT like family A2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See dmrt99B in Genome Data Viewer
Location:
99B8-99B8; 3-99 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.46 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29692591..29697025)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25518313..25522747)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene CAP-D2 condensin subunit Neighboring gene Guanylyl cyclase alpha-subunit at 99B Neighboring gene uncharacterized protein Neighboring gene Odorant-binding protein 99c Neighboring gene long non-coding RNA:CR45569 Neighboring gene Odorant-binding protein 99d

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in sex differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
doublesex-Mab related 99B
Names
CG15504-PA
dmrt99B-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    29692591..29697025
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079825.2NP_524549.1  doublesex-Mab related 99B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524549.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VAI8
    Related
    FBpp0084820, FBtr0085454
    Conserved Domains (2) summary
    cd14417
    Location:378415
    CUE_DMA_DMRTA1; CUE-like DMA domain found in doublesex- and mab-3-related transcription factor A1 (DMRTA1) and similar proteins
    pfam00751
    Location:3783
    DM; DM DNA binding domain