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Dppa5a developmental pluripotency associated 5A [ Mus musculus (house mouse) ]

Gene ID: 434423, updated on 26-Sep-2022

Summary

Official Symbol
Dppa5aprovided by MGI
Official Full Name
developmental pluripotency associated 5Aprovided by MGI
Primary source
MGI:MGI:101800
See related
Ensembl:ENSMUSG00000060461 AllianceGenome:MGI:101800
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Esg1; Dppa5; ecat2
Summary
Enables mRNA binding activity. Acts upstream of or within regulation of gene expression. Located in cytoplasm. Is expressed in several structures, including early conceptus and reproductive system. Orthologous to human DPPA5 (developmental pluripotency associated 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in bladder adult (RPKM 3.0), CNS E18 (RPKM 1.3) and 8 other tissues See more
Orthologs
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Genomic context

See Dppa5a in Genome Data Viewer
Location:
9; 9 E1
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (78274334..78275481, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (78367052..78368199, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene glutathione S-transferase, alpha 2 (Yc2) Neighboring gene CRISPRi-validated DppDn enhancer cluster Neighboring gene CRISPRi-validated DppUp enhancer cluster Neighboring gene oocyte expressed protein

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables mRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
developmental pluripotency-associated protein 5A
Names
ES cell-associated transcript 2 protein
ESG-1
developmental pluripotency associated 5
embryonal stem cell specific gene 1
embryonal stem cell-specific gene 1 protein
mDppa5
protein pH 34

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025274.3NP_079550.2  developmental pluripotency-associated protein 5A

    See identical proteins and their annotated locations for NP_079550.2

    Status: VALIDATED

    Source sequence(s)
    AV457404, AV476247
    Consensus CDS
    CCDS23360.1
    UniProtKB/Swiss-Prot
    Q9CQS7
    Related
    ENSMUSP00000071881.6, ENSMUST00000071991.6
    Conserved Domains (1) summary
    pfam16005
    Location:1192
    MOEP19; KH-like RNA-binding domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    78274334..78275481 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)