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Sult2a5 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5 [ Mus musculus (house mouse) ]

Gene ID: 434264, updated on 8-Feb-2024

Summary

Official Symbol
Sult2a5provided by MGI
Official Full Name
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5provided by MGI
Primary source
MGI:MGI:3648378
See related
Ensembl:ENSMUSG00000078799 AllianceGenome:MGI:3648378
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm15438; EG434264
Summary
Predicted to enable 3'-phosphoadenosine 5'-phosphosulfate binding activity and sulfotransferase activity. Predicted to be involved in several processes, including 3'-phosphoadenosine 5'-phosphosulfate metabolic process; ethanol catabolic process; and thyroid hormone metabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human SULT2A1 (sulfotransferase family 2A member 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward liver adult (RPKM 1.9) See more
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Genomic context

Location:
7 A1; 7 7.96 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (13357892..13404732)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (13623967..13670807)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 44254 Neighboring gene STARR-seq mESC enhancer starr_18080 Neighboring gene binder of sperm protein homolog 2 Neighboring gene STARR-seq mESC enhancer starr_18081 Neighboring gene zinc finger, BED type containing 4, pseudogene 1 Neighboring gene K(lysine) acetyltransferase 6B, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_18082 Neighboring gene STARR-seq mESC enhancer starr_18083 Neighboring gene STARR-seq mESC enhancer starr_18084 Neighboring gene transmembrane protein 167, pseudogene 1 Neighboring gene sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2 Neighboring gene zinc finger, BED type containing 4, pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables 3'-phosphoadenosine 5'-phosphosulfate binding ISO
Inferred from Sequence Orthology
more info
 
enables alcohol sulfotransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables bile-salt sulfotransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables steroid sulfotransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables sulfotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables sulfotransferase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in 3'-phosphoadenosine 5'-phosphosulfate metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in cholesterol metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in ethanol catabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in steroid metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in sulfation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in sulfation ISO
Inferred from Sequence Orthology
more info
 
involved_in thyroid hormone metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in xenobiotic metabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
sulfotransferase family 2A member 1 family member

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001184980.1NP_001171909.1  sulfotransferase family 2A member 1 family member

    See identical proteins and their annotated locations for NP_001171909.1

    Status: VALIDATED

    Source sequence(s)
    AC162521
    Consensus CDS
    CCDS52029.1
    UniProtKB/Swiss-Prot
    P50236, Q05A88
    UniProtKB/TrEMBL
    K7N6K9
    Related
    ENSMUSP00000104165.2, ENSMUST00000108525.4
    Conserved Domains (1) summary
    pfam00685
    Location:34278
    Sulfotransfer_1; Sulfotransferase domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    13357892..13404732
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)