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Pigg phosphatidylinositol glycan anchor biosynthesis, class G [ Mus musculus (house mouse) ]

Gene ID: 433931, updated on 27-Nov-2024

Summary

Official Symbol
Piggprovided by MGI
Official Full Name
phosphatidylinositol glycan anchor biosynthesis, class Gprovided by MGI
Primary source
MGI:MGI:3576484
See related
Ensembl:ENSMUSG00000029263 AllianceGenome:MGI:3576484
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gpi7
Summary
Predicted to enable CP2 mannose-ethanolamine phosphotransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human PIGG (phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group)). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in kidney adult (RPKM 5.9), genital fat pad adult (RPKM 4.9) and 28 other tissues See more
Orthologs
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Genomic context

See Pigg in Genome Data Viewer
Location:
5 F; 5 52.9 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (108460679..108497225)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (108312813..108349359)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 18 Neighboring gene predicted gene 8190 Neighboring gene STARR-seq mESC enhancer starr_13907 Neighboring gene predicted gene, 54303 Neighboring gene down-regulator of transcription 1 Neighboring gene RIKEN cDNA 9330198I05 gene Neighboring gene transmembrane 217, retrotransposed

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Gene trapped (1) 

General protein information

Preferred Names
GPI ethanolamine phosphate transferase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081234.3NP_001074703.1  GPI ethanolamine phosphate transferase 2 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AC124107
    Consensus CDS
    CCDS39203.1
    UniProtKB/TrEMBL
    D3YTQ6, D3Z4I0
    Related
    ENSMUSP00000031189.8, ENSMUST00000031189.14
    Conserved Domains (2) summary
    COG0841
    Location:676733
    AcrB; Multidrug efflux pump subunit AcrB [Defense mechanisms]
    cd16024
    Location:62335
    GPI_EPT_2; GPI ethanolamine phosphate transferase 2; PIG-G
  2. NM_001310689.2NP_001297618.1  GPI ethanolamine phosphate transferase 2 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC124107
    Consensus CDS
    CCDS80354.1
    UniProtKB/TrEMBL
    D3YTQ6, D3Z3Y1
    Related
    ENSMUSP00000113818.2, ENSMUST00000119014.8
    Conserved Domains (1) summary
    cd16024
    Location:62335
    GPI_EPT_2; GPI ethanolamine phosphate transferase 2; PIG-G
  3. NM_001370998.1NP_001357927.1  GPI ethanolamine phosphate transferase 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC124107
    UniProtKB/TrEMBL
    D3YTQ6
    Conserved Domains (1) summary
    cd16024
    Location:62335
    GPI_EPT_2; GPI ethanolamine phosphate transferase 2; PIG-G

RNA

  1. NR_163827.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124107

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    108460679..108497225
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)