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fkh fork head [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43383, updated on 28-Oct-2021

Summary

Official Symbol
fkhprovided by FlyBase
Official Full Name
fork headprovided by FlyBase
Primary source
FLYBASE:FBgn0000659
Locus tag
Dmel_CG10002
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG10002; dFoxA; Dm-FoxA; Dmel\CG10002; Dmfkh; Fkh; FKH; Sebp2
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Genomic context

See fkh in Genome Data Viewer
Location:
98D5-98D5; 3-96 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (28580976..28585264, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (24406698..24410986, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Papilin Neighboring gene mitochondrial translation initiation factor 2 Neighboring gene long non-coding RNA:CR43126 Neighboring gene long non-coding RNA:CR43440

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in DNA endoreduplication IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in Malpighian tubule morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in anatomical structure morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in determination of adult lifespan IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ecdysone-mediated induction of salivary gland cell autophagic cell death IDA
Inferred from Direct Assay
more info
PubMed 
involved_in endoderm formation TAS
Traceable Author Statement
more info
PubMed 
involved_in insulin receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of cell growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of multicellular organism growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of programmed cell death IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of transcription by RNA polymerase II TAS
Traceable Author Statement
more info
PubMed 
involved_in neuroendocrine cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in salivary gland development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in salivary gland morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in polytene chromosome IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
fork head
Names
CG10002-PA
CG10002-PB
CG10002-PC
CG10002-PD
CG10002-PE
fkh-PA
fkh-PB
fkh-PC
fkh-PD
fkh-PE
forkhead
secretion enhancer-binding protein 2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    28580976..28585264 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001300645.1NP_001287574.1  fork head, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287574.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P14734
    UniProtKB/TrEMBL
    E1JJ07
    Related
    FBpp0311419, FBtr0345227
    Conserved Domains (2) summary
    smart00339
    Location:210298
    FH; FORKHEAD
    pfam08430
    Location:120209
    Forkhead_N; Forkhead N-terminal region
  2. NM_001170291.1NP_001163762.1  fork head, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163762.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P14734
    UniProtKB/TrEMBL
    E1JJ07
    Related
    FBpp0289487, FBtr0300259
    Conserved Domains (2) summary
    smart00339
    Location:210298
    FH; FORKHEAD
    pfam08430
    Location:120209
    Forkhead_N; Forkhead N-terminal region
  3. NM_001276109.1NP_001263038.1  fork head, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001263038.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KHC0
    Related
    FBpp0303365, FBtr0330333
    Conserved Domains (2) summary
    smart00339
    Location:210298
    FH; FORKHEAD
    pfam08430
    Location:120209
    Forkhead_N; Forkhead N-terminal region
  4. NM_001316532.1NP_001303461.1  fork head, isoform E [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A126GV17
    Related
    FBpp0312360, FBtr0346765
    Conserved Domains (2) summary
    smart00339
    Location:210298
    FH; FORKHEAD
    pfam08430
    Location:120209
    Forkhead_N; Forkhead N-terminal region
  5. NM_079818.3NP_524542.1  fork head, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524542.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P14734
    UniProtKB/TrEMBL
    E1JJ07
    Related
    FBpp0084690, FBtr0085321
    Conserved Domains (2) summary
    smart00339
    Location:210298
    FH; FORKHEAD
    pfam08430
    Location:120209
    Forkhead_N; Forkhead N-terminal region
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