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Spink14 serine peptidase inhibitor, Kazal type 14 [ Mus musculus (house mouse) ]

Gene ID: 433178, updated on 12-May-2024

Summary

Official Symbol
Spink14provided by MGI
Official Full Name
serine peptidase inhibitor, Kazal type 14provided by MGI
Primary source
MGI:MGI:3646952
See related
Ensembl:ENSMUSG00000051050 AllianceGenome:MGI:3646952
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm5505; EG433178
Summary
Orthologous to human SPINK14 (serine peptidase inhibitor Kazal type 14 (putative)). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See Spink14 in Genome Data Viewer
Location:
18 B3; 18 23.74 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (44160936..44165275)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (44027869..44032208)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41715 Neighboring gene serine peptidase inhibitor, Kazal type 5 Neighboring gene high mobility group box 2 pseudogene Neighboring gene serine peptidase inhibitor, Kazal type 6

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (1) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
serine protease inhibitor Kazal-type 14
Names
Kazal type serine protease inhibitor 5-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039218.2NP_001034307.2  serine protease inhibitor Kazal-type 14 precursor

    See identical proteins and their annotated locations for NP_001034307.2

    Status: VALIDATED

    Source sequence(s)
    AC138293, AV381433
    Consensus CDS
    CCDS37806.1
    UniProtKB/TrEMBL
    B9EJP9
    Related
    ENSMUSP00000057781.3, ENSMUST00000060328.9
    Conserved Domains (1) summary
    cl00097
    Location:5596
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    44160936..44165275
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)