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Prr7 proline rich 7 (synaptic) [ Mus musculus (house mouse) ]

Gene ID: 432763, updated on 5-Mar-2024

Summary

Official Symbol
Prr7provided by MGI
Official Full Name
proline rich 7 (synaptic)provided by MGI
Primary source
MGI:MGI:3487246
See related
Ensembl:ENSMUSG00000034686 AllianceGenome:MGI:3487246
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
XM_484263
Summary
Predicted to enable long-chain fatty acid binding activity; protein tyrosine kinase binding activity; and ubiquitin-like protein ligase binding activity. Involved in T cell differentiation in thymus and alpha-beta T cell differentiation. Predicted to be located in several cellular components, including nucleoplasm; perinuclear region of cytoplasm; and postsynaptic density. Orthologous to human PRR7 (proline rich 7, synaptic). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 5.5), adrenal adult (RPKM 5.2) and 21 other tissues See more
Orthologs
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Genomic context

See Prr7 in Genome Data Viewer
Location:
13 B1; 13 30.06 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (55612080..55620968)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (55464267..55473162)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_34617 Neighboring gene coagulation factor XII (Hageman factor) Neighboring gene STARR-positive B cell enhancer ABC_E8892 Neighboring gene STARR-positive B cell enhancer ABC_E212 Neighboring gene STARR-positive B cell enhancer ABC_E4072 Neighboring gene G protein-coupled receptor kinase 6 Neighboring gene microRNA 6943 Neighboring gene drebrin 1 Neighboring gene microRNA 6944 Neighboring gene PDZ and LIM domain 7 Neighboring gene microRNA 6945

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables long-chain fatty acid binding ISO
Inferred from Sequence Orthology
more info
 
enables protein tyrosine kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
enables ubiquitin-like protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in neuron projection ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
is_active_in postsynaptic density, intracellular component ISO
Inferred from Sequence Orthology
more info
 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 
located_in synapse ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
proline-rich protein 7
Names
synaptic proline-rich membrane protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030296.4NP_001025467.1  proline-rich protein 7

    See identical proteins and their annotated locations for NP_001025467.1

    Status: VALIDATED

    Source sequence(s)
    AK133129, CT009762, CX241234
    Consensus CDS
    CCDS26546.1
    UniProtKB/Swiss-Prot
    Q3V0I2
    UniProtKB/TrEMBL
    B2RSG4
    Related
    ENSMUSP00000046776.8, ENSMUST00000046533.9
    Conserved Domains (1) summary
    pfam11669
    Location:1753
    WBP-1; WW domain-binding protein 1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    55612080..55620968
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)