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LOC4326547 hexokinase-6-like [ Oryza sativa Japonica Group (Japanese rice) ]

Gene ID: 4326547, updated on 16-Jun-2026
Gene symbol
LOC4326547
Gene description
hexokinase-6-like
Locus tag
OSNPB_010742500
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Oryza sativa Japonica Group
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa
Also known as
HXK2; HXK6
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See LOC4326547 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_06 current ASM3414082v1 (GCF_034140825.1) 1 NC_089035.1 (31609322..31613628, complement)
102 previous assembly IRGSP-1.0 (GCF_001433935.1) 1 NC_029256.1 (31009687..31013954, complement)

Chromosome 1 - NC_089035.1Genomic Context describing neighboring genes Neighboring gene elongation factor 2 Neighboring gene probable 3-hydroxyisobutyrate dehydrogenase-like 1, mitochondrial Neighboring gene receptor-like protein kinase HSL1 Neighboring gene uncharacterized LOC107276483 Neighboring gene protein IQ-DOMAIN 25

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Crystal structures of rice hexokinase 6 with a series of substrates shed light on its enzymatic mechanism. He C, et al. Biochem Biophys Res Commun, 2019 Aug 6. PMID 31176485
  2. Pentatricopeptide-repeat family protein RF6 functions with hexokinase 6 to rescue rice cytoplasmic male sterility. Huang W, et al. Proc Natl Acad Sci U S A, 2015 Dec 1. PMID 26578814, Free PMC Article
  3. Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.). Cho JI, et al. Planta, 2006 Aug. PMID 16552590
  4. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Rice Full-Length cDNA Consortium, et al. Science, 2003 Jul 18. PMID 12869764
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. in a conformational study of rice hexokinase 6, residues Gly112, Thr261, Gly262, and Gly450 are essential to the binding between ADP-PO4 and OsHXK6 by a series of single mutations and enzymatic assays
    Title: Crystal structures of rice hexokinase 6 with a series of substrates shed light on its enzymatic mechanism.
  2. Together these results reveal a novel mechanism for CMS restoration by which RF6 functions with OsHXK6 to restore HL-CMS fertility.
    Title: Pentatricopeptide-repeat family protein RF6 functions with hexokinase 6 to rescue rice cytoplasmic male sterility.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables D-glucose binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glucokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glucose 6-phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glucose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
hexokinase-6
Names
Hexokinase-2
LOC_Os01g53930
P0439E07.19
hexokinase 2
putative hexokinase
NP_001384959.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001398030.1 → NP_001384959.1  hexokinase-6

    Status: VALIDATED

    Source sequence(s)
    AY884165, CI566868, CI593021
    UniProtKB/Swiss-Prot
    Q0JJF0, Q8LQ68
    UniProtKB/TrEMBL
    A2WUX9
    Conserved Domains (1) summary
    PLN02405
    Location:49 → 506
    PLN02405; hexokinase

RefSeqs of Annotated Genomes: GCF_034140825.1-RS_2024_06

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM3414082v1 Primary Assembly

Genomic

  1. NC_089035.1 Reference ASM3414082v1 Primary Assembly

    Range
    31609322..31613628 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8LQ68.1 GenPept UniProtKB/Swiss-Prot:Q8LQ68

Gene LinkOut

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Molecular Biology Databases
Research Materials