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His2Av Histone H2A variant [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43229, updated on 5-Sep-2021

Summary

Official Symbol
His2Avprovided by FlyBase
Official Full Name
Histone H2A variantprovided by FlyBase
Primary source
FLYBASE:FBgn0001197
Locus tag
Dmel_CG5499
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
*i H2av; 5499; CG5499; dHis2Av; Dmel\CG5499; gamma-H2Av; gamma-H2AV; gamma-H2AvD; gamma-His2Av; gamma-HIS2AV; gammaH2Av; gammaH2AV; gammaH2ax; gammaH2Ax; H2A; H2A.F/Z; H2a.V; H2A.V; H2A.X; H2A.Z; H2av; H2Av; H2AV; h2AvD; H2avD; H2AvD; H2AV_DROM; H2AX; H2AZ; his; His; HIS; His2; His2A; his2Av; His2av; His2AV; HIS2AV; His2AvD; HIS2AVD; HisH2Av; Hist; Hist2av; l(3)05146; l(3)810; l(3)97Dd; l(3)L1602
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Genomic context

See His2Av in Genome Data Viewer
Location:
97D3-97D3; 3-92 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (26866929..26869220)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (22692651..22694942)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Integrator 12 Neighboring gene ballchen Neighboring gene Secreted protein, acidic, cysteine-rich Neighboring gene Ribonuclear protein at 97D

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the His2Av gene: The His2Av gene is conserved in human, chimpanzee, Rhesus monkey, cow, mouse, rat, zebrafish, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
enables protein-containing complex binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in chromosome IDA
Inferred from Direct Assay
more info
PubMed 
part_of nucleosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in polytene chromosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in polytene chromosome chromocenter IDA
Inferred from Direct Assay
more info
PubMed 
located_in site of double-strand break IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
histone H2A
Names
CG5499-PA
CG5499-PB
H2A
His2Av-PA
His2Av-PB
Histone-2A
Histone-2av
histone
histone
histone 2A
histone H2A.v
histone H2Av
histone2A
histone2Av
histone2AvD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    26866929..26869220
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001276068.1NP_001262997.1  histone H2A variant, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262997.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P08985
    UniProtKB/TrEMBL
    A0A0B4KH25
    Related
    FBpp0306426, FBtr0334311
    Conserved Domains (1) summary
    PLN00154
    Location:6121
    PLN00154; histone H2A; Provisional
  2. NM_079795.3NP_524519.1  histone H2A variant, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524519.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P08985
    UniProtKB/TrEMBL
    A0A0B4KH25
    Related
    FBpp0084434, FBtr0085062
    Conserved Domains (1) summary
    PLN00154
    Location:6121
    PLN00154; histone H2A; Provisional
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