nxf1.S nuclear RNA export factor 1 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: nxf1.S
Official Full Name: nuclear RNA export factor 1 S homeolog
Primary source: Xenbase:XB-GENE-865879
Locus tag: XELAEV_18024209mg
See related: EnsemblRapid:ENSXLAG00005009075 AllianceGenome:Xenbase:XB-GENE-865879
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: nxf1
Summary: Predicted to enable RNA binding activity. Predicted to act upstream of or within mRNA export from nucleus. Predicted to be located in cytoplasm and nucleoplasm. Orthologous to human NXF1 (nuclear RNA export factor 1). [provided by Alliance of Genome Resources, Apr 2025]
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Genomic context

Location:: chromosome: 4S

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	4S	NC_054378.1 (1714314..1745453, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	4S	NC_030731.1 (1711329..1740261, complement)

Chromosome 4S - NC_054378.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within mRNA export from nucleus	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mRNA transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nuclear speck	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: nuclear RNA export factor 1 S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001091506.1 → NP_001084975.1 nuclear RNA export factor 1 S homeolog

See identical proteins and their annotated locations for NP_001084975.1

Status: PROVISIONAL

Source sequence(s)

BC070656

UniProtKB/TrEMBL

A0A974D031, Q6IRQ2

Related

ENSXLAP00005026713.1, ENSXLAT00005027445.1

Conserved Domains (6) summary

smart00804
Location:548 → 613

TAP_C; C-terminal domain of vertebrate Tap protein

sd00035
Location:220 → 262

LRR_NTF; leucine-rich repeat [structural motif]

pfam09162
Location:113 → 194

Tap-RNA_bind; Tap, RNA-binding

pfam12799
Location:287 → 325

LRR_4; Leucine Rich repeats (2 copies)

pfam13855
Location:261 → 323

LRR_8; Leucine rich repeat

cl09109
Location:378 → 529

NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of ...